Recreational Drugs Repurposed for Medicinal Use

Seetal Dodd is Affiliate Professor in the School of Medicine at Deakin University, Melbourne, and at The Institute for Mental and Physical Health and Clinical Translation (IMPACT) at Barwon Health in Geelong, Australia. Michael Berk is currently a NHMRC Leadership 3 research Fellow and is Deakin Distinguished Chair of Psychiatry at Deakin University in Melbourne, and at Barwon Health in Geelong, Australia, where he heads the Institute for Innovation in Mental and Physical Health and Clinical Translation (IMPACT). Stephen M. Stahl is Distinguished Health Sciences Clinical Professor of Psychiatry and Neuroscience at the University of California, Riverside, and Honorary Visiting Senior Fellow in Psychiatry at the University of Cambridge.

• 1. Introduction Seetal Dodd, Stephen M. Stahl and Michael Berk; 2. Ritual to relief: ethical frontiers in repurposing psychoactive substances Emma O'Leary; 3. Psilocybin and hallucinogenic mushrooms Mathieu Fradet, Carlton M. Kelly, Anna J. Donnelly and Trisha Suppes; 4. Ayahuasca: pharmacology, safety, and therapeutic effects Rafael Guimarães dos Santos and Jaime Eduardo Cecilio Hallak; 5. Recreational drugs repurposed for medicinal use-cannabis Mike Armour, Justin Sinclair and Hannah Adler; 6. Ketamine in clinical practice: transitioning from anesthetic agent to psychiatric therapeutic Jose Manuel Quintero, Rosa Helena Bustos, Sharon Lechtig-Wassermann, Stephania Beltran and Carlos A. Zarate, Jr.; 7. MDMA-assisted therapy: challenges, clinical trials, and the future of MDMA in treating behavioral disorders Steve O'Brien and David Nutt; 8. Central nervous system stimulants in recreational and medical use Seetal Dodd, Laura Ospina Pinillos and John Markowitz; 9. From betel nuts to Cobenfy: how an ancient recreational drug gave rise to a new class of schizophrenia medications Justin F. Creeden, Siddharth N. Machiraju, Johansen B. Amin and Stephen M. Stahl.