Realist Trials and Systematic Reviews

Chris Bonell is Professor of Public Health & Sociology in the Department of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine. His research mainly focuses on adolescent health, sexual health and violence. He was involved in scientific advice to the UK government during the Covid-19 pandemic, particularly in the areas of communication strategies and school interventions. G. J. Melendez-Torres is Professor of Clinical and Social Epidemiology at the University of Exeter, where he also holds the citiesRISE Research Chair in Public Mental Health. A registered nurse, his research is primarily in epidemiology and evaluation in child and adolescent health and in intimate partner violence. Emily Warren is an Assistant Professor at the London School of Hygiene and Tropical Medicine, where she evaluates public policies and complex interventions using realist approaches. She is a recipient of the European Society for Prevention Research Presidents' Award in recognition of her work on the philosophical compatibility and feasibility of realist RCTs.

• 1. Introduction; 2. Why are trials and systematic reviews necessary but insufficient to inform health policy?; 3. Realist critiques and manifesto for evaluation and reviews; 4. Building realist theory in evaluations; 5. Refining realist theory through process evaluations; 6. Testing realist theory through trials or other evaluation designs; 7. Building and refining realist theory in systematic reviews; 8. Testing realist theory through synthesising outcome evaluations; 9. Using evidence to inform intervention scale-up and transfer; 10. Using evidence to refine middle range theory; Conclusions.