Reactions and Syntheses

Lutz F. Tietze studied chemistry at the universities of Freiburg and Kiel, Germany, and obtained his doctorate under the supervision of Prof. B. Franck in 1968 in Kiel. He then worked as a research associate with Prof. G. Büchi at MIT, Cambridge, USA, as well as with Prof. A. Battersby in Cambridge, UK. Since 1978 he has been Professor and Head of the Institute of Organic and Biomolecular Chemistry at the Georg-August-University in Göttingen, Germany. He has received many prizes, e.g. the highly prestigious Emil Fischer Medal of the German Chemical Society and has been awarded in 2012 with the position of a Distinguished Research Professor. His research focuses on the development of efficient and selective synthetic methods, combinatorial chemistry, the total synthesis of natural products and the design of new selective anticancer agents. He has over 460 papers, 34 patents and four books to his name.Theophil Eicher studied chemistry at the University of Heidelberg, Germany, and obtaind his Ph.D. under Georg Wittig in 1960. After postdoctoral work at Columbia University, New York, USA, in the laboratories of Ronald Breslow, he habilitated 1967 at the University of Würzburg, Germany, under Siegfried Hünig. In 1974 he was appointed as Associate Professor at the University of Hamburg, in 1976 as Full Professor of Organic Chemistry at the University of Dortmund, Germany. Since 1982, he worked as Full Professor at the University of the Saarland, Germany, and was retired in 2000. His research interests concerned the synthetic chemistry of cyclopropenones and triafulvenes, as well as natural product synthesis in the field of bryophyte constituents. He is co-author of several books. Jointly with L. F. Tietze, he was awarded the literature prize of the "Fonds der chemischen Industrie". He is Dr. h. c. and Prof. a. h. of the Facultad de Quimica of the Universidad de la Republica, Montevideo/Uruguay.Ulf Diederichsen studied Chemistry in Freiburg, Germany, with a diploma work in organic synthesis and completed his Ph.D. in 1993 under the supervision of Albert Eschenmoser at the ETH Zürich working on homo- and glucose-DNA. Following postdoctoral work on radical chemistry at the University of Pittsburgh, USA, in the group of Dennis Curran, he gained his habilitation at the Technical University Munich, Germany, with Horst Kessler as mentor. In 1999, he was appointed professor of Organic Chemistry at the University Würzburg, Germany, until joining the Georg-August-University in Göttingen, Germany, in 2001 as full professor of Organic Chemistry. He was visiting professor at the LMU Munich and Goering Visiting Professor at the University of Wisconsin, USA. In 1999 he got the Karl Winnacker stipend and Hellmut-Bredereck award and is an ordinary member of Göttingen Academy of Sciences and Humanities since 2012.Andreas Speicher studied chemistry at Saarland University,Germany. He obtained his Ph.D. in 1994 under Theophil Eicher and was honoured with the Eduard-Martin-Award of his university. He started his independent scientific career and completed habilitation in 2003 (Privatdozent). He is head of a research group and university lecturer for organic chemistry at the Saarland University and was appointed extraordinary professor in 2011. He is temporary holding a guest professorship at the University of Strasbourg/France since 2006 and is co-author of several books. His research interests are directed to synthesis and characterization of chemically and biologically relevant natural products, especially to axially chiral macrocyclic compounds.

• C-C BOND FORMATIONNucleophilic Addition to Aldehydes, Ketones, Carboxylic Acid Derivatives (Esters, Anhydrides) and alpha,beta-Unsaturated Carbonyl Compounds;Carbonyl OlefinationAlkylation of Aldehydes/Ketones, Carboxylic Acids, and beta-Dicarbonyl CompoundsReactions of the Aldol and Mannich TypeElectrophilic and Nucleophilic AcylationReactions of Alkenes via Carbenium Ions Transition-Metal-Catalyzed ReactionsPericyclic ReactionsRadical Reactions OXIDATION AND REDUCTIONEpoxidation of C=C BondsDihydroxylation of C=C BondsOxidation of Alcohols to Carbonyl CompoundsEnantioselective Reduction of KetonesBiomimetic Reductive AminationEnantioselective Wacker HETEROCYCLIC COMPOUNDSThree- and Four-Membered Heterocycles Five-Membered HeterocyclesSix-Membered HeterocyclesCondensed HeterocyclesOther Heterocyclic Systems;Heterocyclic Dyes SELECTED NATURAL PRODUCTSIsoprenoidsCarbohydratesAmino Acids and PeptidesNucleotides and Oligonucleotides DOMINO REACTIONSDomino Reactions in Synthetic MethodologyDomino Reactions in The Synthesis of AlkaloidsDomino Reactions in The Synthesis of IsoprenoidsDomino Reactions for The Synthesis of Chromans And DioxinsDomino Reactions in The Synthesis of Chiroptical Switches INDEX OF REACTIONSINDEX OF PRODUCTS SUBJECT INDEX