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Marina Ramirez-Alvarado, Jeffery W. Kelly, Christopher M. Dobson - Protein Misfolding Diseases, Inbunden

Inbunden, Engelska, 2010

Del 2 i serien Wiley Series in Protein and Peptide Science

Protein Misfolding Diseases

Current and Emerging Principles and Therapies

Av Marina Ramirez-Alvarado, Jeffery W. Kelly, Christopher M. Dobson

3839 kr

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Beskrivning
An increasingly aging population will add to the number of individuals suffering from amyloid. Protein Misfolding Diseases provides a systematic overview of the current and emerging therapies for these types of protein misfolding diseases, including Alzheimer's, Parkinson's, and Mad Cow. The book emphasizes therapeutics in an amyloid disease context to help students, faculty, scientific researchers, and doctors working with protein misfolding diseases bridge the gap between basic science and pharmaceutical applications to protein misfolding disease.
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MARINA RAMIREZ-ALVARADO is an Assistant professor of Biochemistry and Molecular Biology at the Mayo Clinic. Despite being a young investigator, she is already a world leader in the study of molecular determinants of light chain amyloidosis, a reare misfolding disease. JEFFERY W. KELLY is a Professor of Chemistry and Molecular and Experimental Medicine at the Scripps Research Institute. He is one of the leading authorities in the field of protein misfolding, with over 250 publications to his credit.CHRISTOPHER M. DOBSON is a Professor in the Department of Chemistry at the University of Cambridge. Dr. Dobson is a leading researcher studying the structure and biochemical bases of protein misfolding diseases and has over 500 publications.

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“The book is very well organized and clearly written, and contains a large number of nice figures and illustrations, some in color, which certainly help to simplify the complex thematic material. The contributions provide a sufficient body of background information, are concisely written, and contain many references, which make them valuable bibliographic sources.” (Angewandte Chemie, December 2010) "In this valuable contribution to the understanding of protein- deposition diseases, Ramirez-Alvarado (biochemistry and molecular biology, Mayo Clinic College of Medicine) and international contributors to 45 chapters present an integrated approach to the process and consequences of protein aggregation." (Book News, September 2010)

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