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The two subjects which have been previously widely covered, the roles of prolactin in lactation and in rat mammary cancer, are presented relatively briefly though with a full list of references.
1. Introduction.- Section A: Physiology and Pathophysiology of Prolactin.- 2. Isolation, structure and cells of origin.- 3. Assay of prolactin.- 4. Biochemistry and effects on metabolism.- 5. Effects of metabolic and environmental stimuli on prolactin secretion.- 6. Control of prolactin secretion.- 7. Prolactin in male and female reproduction.- 8. Pregnancy.- 9. Lactation.- 10. Prolactin and thyroid function.- 11. Prolactin and cancer.- 12. Prolactin and fluid and electrolyte balance and the cardiovascular system.- 13. Other effects of prolactin.- Section B: Prolactin and Human Disease.- 14. Introduction. Hormones and disease.- 15. Tests of the prolactin secreting system.- 16. Drugs which alter prolactin secretion.- 17. Puerperal lactation and galactorrhea.- 18. Premenstrual syndrome and pregnancy toxemia.- 19. Disorders of fluid and electrolyte balance.- 20. Nephrotic syndrome.- 21. Thyroid disease.- 22. Adrenal disease.- 23. Hypertension.- 24. Migraine.- 25. Asthma.- 26. Rheumatoid arthritis and collagen disease.- 27. Diabetes mellitus.- 28. Epilepsy.- 29. Natural and drug-induced Parkinsonism.- 30. Myocardial infarction and thrombo-embolic disease.- 31. Mental illness.- 32. Cancer.- 33. Other conditions.- Section C: Hypothesis.- 34. The role of prolactin in human physiology and disease.- References.