Production of Biomass and Bioactive Compounds Using Bioreactor Technology

Kee-Yoeup Paek, Research Center for the Development of Advanced Horticultural Technology, Chungbuk National University, Cheongju 361-763, Republic of Korea.Hosakatte Niranjana Murthy, Department of Botany, Karnatak University, Dharwad 580003, India.Jian-Jiang Zhong, State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dong-Chuan Road, Shanghai 200240, China.

• Part I Bioreactor design, advantages and limitations of bioreactor cultures.-1 Design of bioreactors for plant cell and organ cultures.-2 Disposable bioreactors for cultivation of plant cell cultures.-3 Plant derived bioactive molecules: Culture vessels to bioreactors.- Part II Production of biomass and bioactive compounds from cell suspension cultures.-4 Production of carotenoids using microalgae cultivated in photobioreactors.-5 Submerged fermentation of medicinal fungus Cordyceps sinensis for production of biologically active mycelial biomass and exopolysaccharides.- 6 Ginseng cell culture for production of ginsenosides.-7 Production of biomass and bioactive compounds from cell suspension cultures of Panax quinquefolium L. and Glycyrrhiza uralensis Fisch.-Part III Production of biomass and bioactive compounds from organ cultures – shoot, embryo and adventitious root cultures.-8 Production of caffeic acid derivatives from adventitious root cultures of Echinacea purpurea (L.) Moench.-9 Adventitious root culture of Morinda citrifolia in bioreactors for production of bioactive compounds.-10 Production of biomass and bioactive compounds in adventitious root cultures of Eleutherococcus koreanum Nakai.-11 Production of adventitious root biomass and bioactive compounds from Hypericum perforatum L. through large scale bioreactor cultures.-12 Production of withanolides from cell and organ cultures of Withania somnifera (L.) Dunal.-13 Production of bioactive compounds of Siberian ginseng from somatic embryo suspension cultures in bioreactors.-14 Bioreactor culture of shoots and somatic embryos of medicinal plants for production of bioactive compounds.-15 Hairy roots: Production of metabolites to environmental restoration.-16 Mass production of Lilium bulbelets in bioreactors.-17 In vitro production of Digitalis purpurea biomass using temporary immersion cultures.-18 Role of nitric oxidein adventitious roots development.-19 Melatonin-rich plants: Production, significance in agriculture and human health.-Part IV Strategies for production of bioactive compounds, large-scale cultures and metabolic engineering of selected metabolites.-20 Strategies for enhanced production of plant secondary metabolites from cell and organ cultures.-21 Metabolic engineering of selected secondary metabolites.-22 Theoretical basis of plant cell and tissue culture for production of biomass and bioactive compounds.-23 Isoprenoid production via plant cell cultures: biosynthesis, accumulation and scaling-up to bioreactors.-24 Production of ginsenosides from adventitious root cultures of Panax ginseng.-Part V Bio-safety assessments of plant cell and organ culture products.-25 Food ingredients from plant cell, tissue and organ cultures: biosafety and efficacy evaluations.-Part VI Physiological disorders in plants cultured in bioreactors.-26 Biochemical and physiological aspects of hyperhydricity in liquid culture system