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Some forms of cancer biotherapy use the strategy of tumor stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes.This textbook illustrates new methods of thinking and new strategies for control of cancer.
Cancer biotherapy: general principles.- The pathogenesis of cancer metastasis: relevance to therapy.- Developmental therapeutics and the design of clinical trials.- Recombinant proteins and genomics in cancer therapy.- Current concepts in immunology.- Therapeutic approaches to cancer-associated immune suppression.- Cancer vaccines.- Cytokines.- Interferons: therapy for cancer.- Monoclonal antibody therapy.- Immunotoxins.- Drug Immunoconjugates.- Targeted radionuclide therapy of cancer.- Stem cell/bone marrow transplantation as biotherapy.- Cellular immunotherapy (CI), where have we been and where are we going?.- Growth and differentiation factors as cancer therapeutics.- Granulocyte colony-stimulating factor: biology and clinical potential.- Granulocyte-macrophage colony-stimulating factor.- Cancer gene therapy.- Regulatory process for approval of biologicals for cancer therapy.- Cancer biotherapy: 2009 disease-related activity.- Biological therapy of melanoma.- Biological therapy of genitourinary cancer.- Biological therapy of colon cancer.- Biological therapy of breast cancer.- Biological therapy of lung cancer.- Biological therapy of B and T cell lymphoproliferative disorders.- Biological therapy of multiple myeloma.- Biological therapy of squamous cell cancers of the head and neck.- Biological therapy of glioblastoma.- Speculations for 2009 and beyond.