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This book is a guide to foetal medicine for practising obstetricians. Its key aim is to help improve prenatal and perinatal management of high risk pregnancies, with an emphasis on monitoring and diagnosis. Beginning with an overview of prenatal diagnosis, the following sections cover prenatal counselling, non-invasive prenatal screening, invasive diagnostic techniques, laboratory techniques, antenatal use of foetal therapy, prenatal operative scope, ethical and medicolegal aspects, and the future of prenatal diagnosis. The final section offers FIGO best practice guidelines.This comprehensive guide is highly illustrated with more than 350 clinical photographs, figures and tables.Key PointsPractical guide to foetal medicine for practising obstetriciansKey aim to help improve prenatal and perinatal management of high risk pregnanciesIncludes FIGO best practice guidelinesHighly illustrated with more than 350 photographs, figures and tables
Raju R Sahetya MD DGO DFP FCPS FICOGPractising Gynaecologist, Pushpa Hospital, Mumbai, Maharashtra, India Jaideep Malhotra MBBS MD FICOGProfessor, Dubrovnik International University, Dubrovnik, Croatia; Managing Director, ART Rainbow-IVF, Agra, Uttar Pradesh, IndiaHema Purandarey MSMumbai, Maharashtra, India
Section 1: General Aspects of Prenatal DiagnosisRevolution in Prenatal DiagnosisMultidisciplinary Approach for Prenatal Screening and DiagnosisGoals and Issues in The Delivery of Genetic Services in IndiaPrenatal Diagnosis: Challenges and Opportunities Obstetrician Perspective Section 2: Prenatal Genetic CounselingGenetic CounselingPremarital and Preconception CounselingGenetic Counseling in Prenatally Diagnosed Chromosomal AbnormalitiesPreconceptional Counseling and ManagementRole of Genetics in Reproductive FailureGenetics and Counseling of Female Hereditary Breast and Ovarian Cancers Section 3: Prenatal Screening Non-InvasiveGlobal Rainbow HealthcareFirst Trimester ScreeningMaternal Serum Screening for Chromosomal AbnormalitiesNewborn ScreeningScreening and Diagnosis of Inborn Errors of Metabolism11 to 13Weeks Scan: A Window to Fetal AbnormalitiesFetal Anomaly ScanFetal Growth RestrictionColor Doppler in Fetal Growth Restriction Section 4: Diagnostic Techniques Invasive General Principles of Prenatal Diagnosis: Invasive Prenatal DiagnosisChorionic Villus SamplingAmniocentesisCordocentesisFetoscopy Section 5: Laboratory Techniques Genetic Testing: Indications, Types and PrinciplesPreimplantation Genetic Diagnosis:Intrauterine Infections Leading to Increased Fetal Morbidity and Mortality Section 6: Antenatal Use of Fetal Therapy Principles of Fetal Therapy and Multifetal Pregnancy ReductionIntrauterine TransfusionManagement of Multifetal PregnanciesTwin To Twin Transfusion SyndromePregnancy and Antiepileptic Drug Treatment Section 7: Prenatal Operative Scope Principles of Fetal SurgeryFetal Surgery: Why, When and Where?Prenatal Diagnosis and Postnatal Therapy of Surgical AnomaliesFetal Autopsy for Better Prenatal Diagnosis: Illustrative Cases Section 8: Ethical and Medicolegal Aspects Ethical And Medicolegal Issues of Prenatal Genetic DiagnosisAmended Pre-Conception and Pre-Natal Diagnostic Techniques Section 9: The Future of Prenatal Diagnosis Current Status Of Fetal Genomic Diagnosis in Fetal Medicine, Progress And ChallengesArray-Based Comparative Genomic Hybridization (Array Cgh): Future in Prenatal DiagnosisWhat is the Future? Section 10: Guidelines FIGO: Good Practice AdviceFIGO: Best Practice In Maternal Fetal Medicine 2015 Appendix I: Growth Charts