Akademibokhandeln
J. Andrew Williams, J. Andrew Williams, Richard Lalonde, Jeffrey R. Koup, David D. Christ - Predictive Approaches in Drug Discovery and Development, Inbunden

Inbunden, Engelska, 2012

Del 11 i serien Wiley Series on Technologies for the Pharmaceutical Industry

Predictive Approaches in Drug Discovery and Development

Biomarkers and In Vitro / In Vivo Correlations

Av J. Andrew Williams, J. Andrew Williams, Richard Lalonde, Jeffrey R. Koup, David D. Christ

2389 kr

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Beskrivning
Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers.  Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics biomarkers.  Regulatory agency perspectives and initiatives both in the US and internationally are also discussed.
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J. Andrew Williams, PHD, is Director of Translational Oncology at Pfizer Oncology.Richard Lalonde, PharmD, is Vice President and Global Head of Clinical Pharmacology at Pfizer.Jeffrey Koup, PharmD, is a consultant for PKPD modeling and the owner of Lakeside PKPD, LLC.David D. Christ, PHD, is a consultant with SNC Partners LLC.

Recensioner i media

“The ability to correlate in vitro and in vivo biomarker information in the process of drug discovery and development lies at the heart of translational research. The goal is to rapidly translate basic discoveries into clinical applications. This book provides state-of-the-art information on this exciting new research approach.”  (Doody’s, 8 February 2013)“The text is packed with interesting, comprehensive, and pertinent information, clearly presented with salient points reinforced by inclusion in text boxes . . . This is an admirable textbook for those dealing with drug discovery and development. I enjoyed reading through it and I would recommend it to anyone who has an interest, or is developing an interest, in the field of biomarkers and their, as yet, unfulfilled potential.”  (ISSX International Society for the Study of Xenobiotics, 1 December 2012)

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