Precision Molecular Pathology of Myeloid Neoplasms

Chung-Che (Jeff) Chang, MD, PhDProfessor of PathologyUniversity of Central Florida;Medical Director, Hematology and Molecular Pathology LabsFlorida HospitalOrlando, FloridaRobert S. Ohgami, MD, PhDAssistant Professor of PathologyAssociate Program Director for Anatomic PathologyDepartment of PathologyStanford UniversityStanford, California

• Acute myeloid leukemia (AML) with recurrent cytogenetic abnormalities.- AML with characteristic molecular mutations: RUNX1, CEPA, NPM1, etc.- AML, NOS/AML with dysplasia-related changes/therapy-related myeloid neoplasm.- Myelodysplastic syndromes (MDS).- Chronic myelogenous leukemia (CML).- Polythesemia vera (PV).- Essential thrombocythemia (ET).- Primary myelofibrosis (PMF).- Mastocytosis.- Myeloproliferative neoplasms (MPN), rare types (Chronic eosinophilic leukemia, Chronic neutrophilic leukemia).- Atypical CML.- Chronic myelomonocytic leukemia (CMML).- Juvenile myelomonocytic leukemia (JMML).- Childhood MDS.- Familial AML/MPN/MDS.- Myeloid and lymphoid neoplasm with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1.