Precision Molecular Pathology of Breast Cancer

Ashraf Khan, MD, FRCPathUniversity of Massachusetts Medical School, Department of Pathology, Worcester, MA, USAIan O. Ellis, MD, FRCPathUniversity of Nottingham, Department of Histopathology, Nottingham City Hospital, Nottingham, UKAndrew M. Hanby, BM, FRCPathSt. James University Hospital/University of Leeds, Leeds Institute of Cancer and Pathology, Leeds, West Yorkshire, UKEdiz F. Cosar, MDUMassMemorial Medical Center, University of Massachusetts Medical School, Department of Pathology, Worcester, MA, USAEmad Rakha, MD, PhD, FRCPathUniversity of Nottingham, Department of Histopathology, Nottingham City Hospital, Nottingham, UKDina Kandil, MDUMassMemorial Medical Center, University of Massachusetts Medical School, Department of Pathology, Worcester, MA, USA

• Molecular basis of breast cancer imaging.- Familial Breast Cancer and Genetic Predisposition in Breast Cancer.- Modelling the Molecular Pathology of Breast Cancer Initiation.- Molecular Pathology of Precancerous Lesions of the Breast.- Breast Cancer Stem Cells: Role in Tumor Initiation, Progression and Targeted Therapy.- Molecular Pathology of Pre-Invasive Ductal Carcinoma. -Molecular Pathology of Lobular CarcinomaAli Sakhdari, Lloyd Hutchinson, Ediz Cosar.- Molecular Pathology of Hormone Regulation in Breast Cancer: Hormone Receptor Evaluation and Therapeutic Implications.- Molecular Pathology of HER Family of Oncogenes in Breast Cancer: HER-2 Evaluation and Role in Targeted Therapy.- Molecular Classification of Breast Cancer.- Triple Negative Breast Cancer: Subtypes with Clinical Implications.- Molecular-based Diagnostic, Prognostic and Predictive Tests in Breast Cancer.- Role of MicroRNAs in Breast Cancer.- Molecular Pathology of Fibroepithelial Neoplasms of the Breast.- Molecular Features of Mesenchymal Tumors of the Breast.- Molecular Pathology of Breast Cancer Metastasis.- The molecular pathology of chemoresistance during the therapeutic response in breast cancer.- The Molecular Pathology of Male Breast Cancer.- Specimens for Molecular Testing in Breast Cancer.

“For pathologists andother physicians looking for a good, comprehensive reference on the molecularpathology of breast lesions, this book offers a good summary of this complexfield. Chapters are overall well written, making this a reader friendlyresource for pathologists who deal with the interpretation of these molecularfindings. This book would be a valuable addition to a departmental and personallibrary.” (Ana G. Yuil-Valdes, Doody’s Book Reviews, November, 2015)