Pratt's Essential Biochemistry, Global Edition

Charlott Pratt received her Ph.D. in biochemistry from Duke University. She did post-doctoral research at the University of North Carolina at Chapel Hill and has contributed to numerous primary research articles and reviews. She is presently in the Department of Chemistry at Seattle Pacific University. She is co-author with Donald Voet and Judith Voet of Fundamentals of Biochemistry, also published by Wiley.Kathleen Cornely received her Ph.D. in biochemistry from Cornell University. She has published numerous research articles and is presently Professor in the Department of Chemistry and Biochemistry at Providence College. She is a member of the Educational and Professional Development Committee of the American Society for Biochemistry and Molecular Biology and is on the editorial borad for the journal, Biochemistry and Molecular Biology Education.

• PREFACE xiUnit 1 Introduction1 The Chemical Basis of Life 12 Aqueous Chemistry 24Unit 2 Biomolecules: Structure and Functions3 Flow of Genetic Information 524 Structure of Proteins 855 Functions of Proteins 1196 How Enzymes Work 1547 Enzyme Kinetics and Inhibition 1838 Lipids and Biological Membranes 2159 Transport Through Membrane 23510 Biochemical Signaling 26011 Carbohydrates 283Unit 3 Metabolism12 Metabolism and Bioenergetics 30113 Glucose Metabolism 32914 The Citric Acid Cycle 36215 Oxidative Phosphorylation 38516 Photosynthesis 41117 Lipid Metabolism 43218 Nitrogen Metabolism 46419 Mammalian Fuel Metabolism: Regulation 497Unit 4 Gene Replication and Expression20 DNA Replication and Repair 51921 Transcription and RNA 55122 Synthesis of Proteins 580GLOSSARY G-1ODD-NUMBERED SOLUTIONS S-1INDEX I-1