Porous Silicon for Biomedical Applications

Prof. Santos (D.Sc. Tech., Chem. Eng.) is a Full Professor in Department of Biomedical Engineering at the University of Groningen. He is also Research Director at the University of Helsinki, Faculty of Pharmacy. Prof. Santos is also the co-founder of the startups Capsamedix Oy and Medixmicro Oy, and Coordinator of MSCA-ITN P4 FIT network in tendon repair (~4.1 m€). He holds Visiting Professorships at the Shanghai Jiao Tong University School of Medicine and University of Tartu. Prof. Santos research interests include the development of nanoparticles/nanomedicines and biomaterials for biomedical applications, particularly cancer and heart diseases. His lab makes the unique bridge between medical engineering, pharmaceutical nanotechnology and tissue engineering by combining unique techniques to develop novel therapeutic formulations for translation into the clinic. He is also in Editorial board member of several international journals, and Associate Editor of Nano Select, Smart Materials in Medicine, and Drug Delivery and Translational Research, among others. Prof. Santos has received prestigious awards/grants, for example, the "Talent Prize in Science" in 2010 attributed by the Portuguese Government, ERC Starting Grant in 2013 and ERC Proof-of-Concept Grant in 2018, Young Researcher Award in 2013 attributed by Faculty of Pharmacy, the Academy of Finland Award for Social Impact in 2016, and the CRS Young Investigator Award 2021.

• IntroductionH.A. SantosPart I: Fundamentals of porous silicon for biomedical applications1. Thermal stabilization of porous siliconJ. Salonen and E. Mäkilä2. Thermal properties of nanoporous silicon materialsN. Koshida3. Photochemical and nonthermal chemical modification of porous siliconK.W. Kolasinski4. Protein-modified porous silicon optical devices for biosensingM. Terracciano, C. Tramontano, R. Moretta, B. Miranda, N. Borbone, L. De Stefano, and I. Rea5. Biocompatibility of porous siliconI.S. Naiyeju and L.M. BimboPart II: Porous silicon for bioimaging and biosensing applications6. Optical properties of porous silicon materialsV. Torres-Costa and R.J. Martín-Palma7. Radiolabeled porous silicon for nuclear imaging and theranostic applicationsM. Sarparanta and A.J. Airaksinen8. Porous silicon for targeting microorganisms: Detection and treatmentN. Massad-Ivanir, S. Arshavsky-Graham, and E. Segal9. Porous silicon biosensors for DNA sensingG.A. Rodriguez, J.L. Lawrie, R. Layouni, and S.M. Weiss10. Near-infrared imaging for in vivo assessment of porous silicon-based materialsB. Xia, J. Li, and Y. Gao11. Porous silicon-based sensors for protein detectionE.E. Antunez, M.A. Martin, and N.H. VoelckerPart III: Porous silicon for drug delivery, cancer therapy, and tissue engineering applications12. Nanoporous silicon to enhance oral delivery of poorly water-soluble drugsH.B. Schultz, P. Joyce, C.A. Prestidge, and T.J. Barnes13. Porous silicon for tumor targeting and imagingJ.-H. Park, M. Jeong, and H. Kim14. Porous silicon-polymer composites for cell culture and tissue engineeringS.J.P. McInnes, R.B. Vasani, N.K. McMillan, and N.H. Voelcker15. Porous silicon and related composites as functional tissue engineering scaffoldsN.K. McMillan and J.L. Coffer16. Porous silicon in photodynamic and photothermal therapyL.A. Osminkina and M.B. Gongalsky17. Porous silicon microneedles and nanoneedles for biomedical applicationsC. Chiappini18. Porous silicon materials for cancer and immunotherapyF. Fontana, Z. Liu, J. Hirvonen, and H.A. Santos