Polymorphism in Molecular Crystals

Joel Bernstein earned his Ph.D. in physical chemistry at Yale University for research on solid-state spectroscopy of organic compounds. Following postdoctoral stints at UCLA and the Weizmann Institute of Science, he joined the faculty of the newly established Ben-Gurion University of the Negev, where until 2010 he was the Carol and Barry Kaye Professor of Applied Science in the Chemistry Department. From 2010-2016, he was Global Distinguished Professor of Chemistry at New York University, both in Abu Dhabi and Shanghai. His research interests center on the organic solid state, with emphasis on understanding and utilizing polymorphism, structure-property relationships, hydrogen-bonding patterns and graph sets and organic conducting materials. He has published nearly 200 research and review articles and chapters on these subjects. He has served as a consultant to many multinational pharmaceutical companies and as a testifying witness in patent litigations on the solid-state chemistry of drugs.

• 1: Introduction and historical background2: Fundamentals3: Exploring the crystal form landscape4: Analytical techniques for studying and characterizing polymorphs and polymorphic transitions5: Computational aspects of polymorphism6: Polymorphism and structure-property relations7: Polymorphism of pharmaceuticals8: Polymorphism of pigments and dyes9: Polymorphism of high energy materials10: Polymorphism and patents

excellent and very informative. . . Many well selected examples are discussed which guide a new researcher into the field. It is also a fantastic source of historical, fundamental and up to date papers and reviews (110 pages of references). This book then can be read by a beginner in the field but also by an active researcher in polymorphism, crystal engineering or crystal chemistry.