Polymeric Nanoparticles as a Promising Tool for Anti-cancer Therapeutics

Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya, Sagar, Madhya Pradesh, India. He has more than 12 years of teaching, research, and industrial experience at international levels from various countries, including the United States, Malaysia, and India. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has more than 350 international publications in well-reputed journals and more than 25 international books (Elsevier). He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award”, most prestigious “SERB-Ramanujan Fellowship Award”. He actively participates in outreach and scientific dissemination for the service of the wider community. His Number of citations is = 26779; h-index = 85; i-10 index = 370 (According to google scholar on March 2025). He has more than 30 international publications published in very high impact factor journals (Progress in Polymer Sciences IF 32.063, Molecular Sciences IF 41.444, Progress in Material Sciences IF 48.580, Advanced Materials IF 29.4, Drug Resistance Update IF 22.841 and Material Todays IF 32.072). He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community. Dr. Kishore M. Paknikar is Professor Agharkar Chair and former Director of Agharkar Research Institute, Pune, India. He is a MSc in Microbiology (1980) and a PhD in Microbiology (1984) from the University of Poona, India. His work in the field of delivery systems focuses on the delivery of drugs, proteins, peptides, siRNA, and nutrients. He is also exploring systems like polymeric nanoparticles and dendrimers for delivery of bioactive molecules in the treatment of cancers, Alzheimer’s disease, candidiasis, etc. He has more than 120 publications in highly reputed journals and 33 patents to his credit. He was a visiting Professor at Louis Pasteur University (Strasbourg, France) and Wayne State University (School of Medicine, Detroit, USA). He also worked as a Research Advisor at National Nanotechnology Centre (Ministry of Science and Technology), Bangkok, Thailand. He has several fellowships and awards to his credit. Dr. Virendra Gajbhiye has been working in the field of nanomedicine for the last 15 years. He has a doctoral degree (Ph.D.) in Pharmaceutical Science with post-doctoral research experience at University of Wisconsin-Madison and Oregon Health and Sciences University. Since 2013 he is working as a Scientist in Nanomedicine at Agharkar Research Institute, Pune, India. He has worked extensively with polymeric nanoparticles specially dendrimers and mesoporous silica nanoparticles. His research interest lies in Nanomedicine, Targeted drug and siRNA delivery, Biomedical application of dendrimers, Biomaterials unimolecular micelles and imaging, Multifunctional polymeric nanoparticles, Nanoparticles in tissue engineering.

• 1. Current status and future challenges of various polymers as cancer therapeutics2. An overview of polymeric nanoparticles as potential cancer therapeutics3. Poly acrylate (e.g., poly methylacrylate, poly ethyl acrylate, etc.) nanoparticles as promising tool for anticancer therapeutics4. Poly (alkyl cyano acrylate) nanoparticles as promising tool for anticancer therapeutics5. Poly (α-hydroxy acids) based nanoparticles for Drug/Gene delivery for cancer therapy6. Poly (ester), Poly hydroxy alkanoate nanoparticles as promising tool for anticancer therapeutics7. Poly (phospho ester), Poly (phosphazene) nanoparticles as promising tool for anticancer therapeutics8. Poly (carbonate) nanoparticles as promising tool for anticancer therapeutics9. Poly (amino acid) nanoparticles as promising tool for anticancer therapeutics10. Poly ethylene glycol nanoparticles as promising tool for anticancer therapeutics11. Dendrimer (polyamidoamine, polypropylene imine, poly-L-lysine, carbosilane dendrimers, triazine dendrimers) as promising tool for anticancer therapeutics12. Conjugated polymer nanoparticles as promising tool for anticancer therapeutics13. Microbes based natural polymer (Xanthum gum, alginate, gellan gum, carrageenan) nanoparticles as promising tool for anticancer therapeutics14. Plant based natural polymer (Guar gum, pectin, starch, cellulose, cyclodextrins) nanoparticles as promising tool for anticancer therapeutics15. Animal based natural polymer (Gelatin, chitosan, albumin, hyaluronic acid, chondroitin sulphate) nanoparticles as promising tool for anticancer therapeutics16. Polymersomes as promising tool for anticancer therapeutics17. Other polymers (Poly sulfonic acids, Poly carboxylic acids, Poly boronic acid, Poly silamine, etc.) nanoparticles as promising tool for anticancer therapeutics18. Conclusion and future prospective of polymeric nanoparticles as cancer therapeutics