Plant-Based Drug Discovery

Dr. Mamta Bisht is presently working as an Assistant Professor in the Department of Chemistry, School of Applied and Life Sciences, Uttaranchal University (NAAC A+), Dehradun, Uttarakhand, India. She has been actively involved in the extraction, isolation, and characterization of “natural products” obtained from the medicinal and aromatic plants with bioactivity for the last 8 years. Besides this, her analytical skills are in GC, GC-MS, HPLC, Prep-HPLC, and HPTLC. Furthermore, she is equally involved in the promotion of endangered and economically important species from the youngest Himalayan region. She has published more than 20 papers in peer-reviewed international journals and seven book chapters. Further, she has participated in more than 10 conferences, including national and international ones. She is a lifetime member of the Indian Science Congress Association. Under her guidance, many PG and UG students successfully completed their project thesis, and some PhD students are currently working with her Prof (Dr.) Ajay Singh is currently working as Director SALS and Dean Research & Studies in Uttaranchal University, Dehradun, India. He has more than 20 years (including R&D industrial research) of research experience. He has published more than 70 research articles in reputed journals and several chapters during his research work. More than 5 patents and projects are also credited in his account. He has also written 2 academic books for UG and PG students. He has guided more than 50 students for Project thesis of U.G and P. G. students and awarded more than 5 Ph. D students and several are registered under him. He is the receipt of young Scientist award by Scientific Planet Society India and several other awards.Dr. Akhileshwar Kumar Srivastava works as a Research Associate (ICMR) at CSIR-Central Food Technological Research Institute, Mysore, India. In his 11 years of research, he has published more than 18 research articles in reputed international journals, along with 4 books and 11 book chapters. His research specialization is primarily in the area of pharmacognosy with genetics, metabolomics, bioinformatics, and molecular biology associated with targeting virulent factors of diseases. In addition, he has studied at Augusta University (formerly, Georgia Regents University) in Augusta, GA, USA, on a J-1 Exchange Scholar Visa and at Ben-Gurion University, Israel. He is also a life member fellow in the Indian Science Congress and the Agriculture, Nutrition and Health Academy, UK.

• Section I: Introduction1. Overview of lifestyle-related metabolic disordersSection II: Phytochemicals and molecular targets2. Significance of phytochemicals in metabolic disorders3. Exploring the role of phytochemicals in managing metabolic disorders4. Enhancing understanding of phytochemicals’ role in managing metabolic disorders5. Molecular connection of oxidative stress and metabolic syndrome: Therapeutic role of phytocomponents6. Epigenetics mechanisms of phytochemicals in cure of metabolic diseases7. Unlocking the epigenetic potential: Phytochemicals as agents in the treatment of metabolic diseases8. Plant–derived bioactive peptides for treatment of metabolic disorders9. Efficiency of phytochemicals to cure metabolic diseases by targeting mitophagy10. The Potential of phytochemicals in mitophagy-driven treatment of metabolic diseases11. Phytochemicals as promising therapeutic approaches for inflammasomes-related metabolic disorders12. Regulatory Impact of phytochemicals on metabolic diseases by targeting Nrf2-ARE signaling mechanism13. Targeting molecular chaperones with phytochemicals for drug discovery in metabolic ailmentSection III: Nanotechnology methods14. Molecular targets of plant nutraceuticals against obesitySection IV: Clinical study15. Navigating molecular targets: plant nutraceuticals in the battle against obesitySection V: Technologies and challenges for plant-based drug discovery16. Molecular insight to cure cardiovascular diseases through plant compounds17. Mechanistic insights of important medicinal plant compounds in managing type 2 diabetes mellitus18. Nanotechnological aspects in the development of phyto-therapeutics against metabolic disorders19. New opportunities and challenges for improving the druggability of plant product against metabolic disorders20. Clinical evidences of phytochemicals in cure of metabolic diseases21. Integration of artificial intelligence with traditional medicine for treating diabetes22. Integration of high-throughput omics technologies in discovery of phytodrugs to treat metabolic diseases23. Multitargets drug design for screening of phytochemicals to cure of metabolic disorders24. New opportunities and challenges for improving the drug ability of plant products against metabolic disorders