Medieval historian Aberth presents interactions of humans and epidemics in case studies of six infectious diseases: plague, smallpox, tuberculosis, cholera, influenza, and AIDS. He chose these because they have known pathogens, can be fatal, and have had long histories. Not merely narrative or descriptive, his study is an attempt to demonstrate how human reactions and attitudes to these diseases have in turn shaped how they affect human communities. Going beyond an exercise in the social construction of disease, Aberth's historical focus on the interaction of disease and human response leads him to be optimistic about human abilities to adjust to and even neutralize biomedical effects. The longest chapter, on the plague, reflects the author's professional specialty. The second longest chapter is on AIDS; remaining chapters are 9-24 pages. Aberth's detailed attention to Islamic understandings of and reactions to plague is especially welcome. He opens each chapter by describing the disease and its effects, then for each disease develops unique reactions and attitudes as well as points introduced earlier, weaving an overall pattern of human progress and intransigence, of connections made and opportunities missed. Summing Up: Highly recommended.