Phytopharmaceuticals for Brain Health

Dr. Shahnaz Subhan, is a researcher and faculty in university settings. She received her PhD in 2002 at the University of Delhi, India. During her PhD, Dr. Subhan has mainly worked on cutting edge research on phytopharmaceuticals for neurological disorders and major skin diseases mainly vitiligo and psoriasis. Her research work was involved in the purification of beta-bungarotoxin binding protein from human cadaver skeletal muscle for neuromuscular disorders. She was also involved in in vitro production of asiatic acid and asiaticoside - highly potent pharmaceutical bioactive compounds known to cure neurological disorders and for in vitro production of psoralen, which is highly expensive and the only compound known to be very effective in the treatment of several skin diseases. Long-term goal of her research group is to provide the groundwork to streamline, accelerate, and promote the translation of basic discoveries into highly effective phytotherapies to benefit humans affected with major neurological and skinrelated problems.She worked as an Assistant Professor with more than nine years of experience in teaching and research at Amity Institute of Biotechnology, Amity University, Uttar Pradesh, India. She also worked as a Principal Investigator for an independent government funded projects in India and Supervisor for PhD and post graduate students of Biotechnology programs at University system in India.Manashi Bagchi, Ph.D., FACN, received her Ph.D. degree in Chemistry in 1984. Dr. Bagchi is currently the Chief Scientific Officer of Dr. Herbs LLC, Concord, CA. Dr. Bagchi served as Associate Professor in the Creighton University School of Pharmacy & Allied Health Profession, Omaha, NE, from Sept 1990 to Aug 1999. Later, she served as the Director of Research at InterHealth Nutraceuticals, Benicia, CA, from Sept 1999 to July 2009. Dr. Bagchi is a Member of the Study Section and Peer Review Committee of the National Institutes of Health (NIH), Bethesda, MD. Her research interests include free radicals, human diseases, carcinogenesis, anti-ageing and anti-inflammatory pathophysiology, mechanistic aspects of cytoprotection by antioxidants and chemoproteactants, regulatory pathways in obesity and gene expression. She is a Member of Society of Toxicology (Reston, VA), New York Academy of Sciences (New York, NY) and Institutes of Food Technologists (Chicago, IL). She is a Fellow and currently Board Member of the American College of Nutrition (Clearwater, FL). Dr. Bagchi has 210 papers in peer reviewed journals and 2 books. She has delivered invited lectures in various national and international scientific conferences, organized workshops, and group discussion sessions. Dr. Bagchi is a Member of the Board of Directors of American College of Nutrition, Clearwater, FL. Dr. Bagchi is serving as Editorial Board Member of the Journal of the American College of Nutrition. Dr. Bagchi received funding from various institutions and agencies including the U.S. Air Force Office of Scientific Research, Nebraska State Department of Health, and Cancer Society of Nebraska.

• ContentsPrefaceEditorsContributorsSection I PathophysiologyChapter 1 A Hidden Etiological Nemesis of Chronic Neurodegenerative DiseasesBernard W. Downs and Manashi BagchiChapter 2 Modulation of Brain Function with Special Emphasis to Hypothalamic–Pituitary–Gonadal Axis by Xenohormones, Phytohormones, and InsulinSanjoy Chakraborty, Devya Gurung, Soheli A. Chowdhury, and Majeedul H. ChowdhuryChapter 3 Environmental Pollution and Climate Change Impacts on Human Health with Particular Reference to Brain: A ReviewMonowar Alam Khalid and Syed Monowar Alam ShahidChapter 4 Metal Toxicity and Oxidative Stress in the Brain: Role of AntioxidantsRama Nair, Manashi Bagchi, and Sreejayan NairSection II PhytopharmaceuticalsChapter 5 Effects of Dietary Supplements and Nutraceuticals of Plant Origin on Central and Peripheral Nervous System PathologyOdete MendesChapter 6 Huperzine A and Shankhapushpi in Brain HealthDebasis Bagchi, Manashi Bagchi, and Anand SwaroopChapter 7 Resveratrol and DepressionJui-Hu Shih, Chien-Fu Fred Chen, and I-Hsun LiChapter 8 Current Perspectives on the Beneficial Role of Curcuma longa and Centella asiatica Linn in Neurological DisordersShahnaz Subhan, Manashi Bagchi, and Abdul IlahChapter 9 Tocotrienol Vitamin E in Brain HealthRichard Stewart and Savita KhannaChapter 10 Emerging Roles of Flavonoids in Brain HealthArti Parihar and Andrea I. DoseffChapter 11 Nuts and Brain HealthSui Kiat Chang and Cesarettin AlasalvarChapter 12 Science behind Usefulness of Bacopa monnieri for Memory and CognitionChandrasekaran Prasanna Raja, Bethapudi Bharathi, Chinampudur Velusami Chandrasekaran, Nithyanantham Muruganantham, Mundkinajeddu Deepak, and Agarwal AmitChapter 13 Food-Derived γ-Aminobutyric Acid Improves the Mental StateHiroshi ShimodaChapter 14 Walnut (Juglans regia L) and Its Neuroprotective Action Mechanism on Brain: A ReviewAbdul Ilah, Akhtaruzzaman, Sabia Bano, Faisal Ismail, and Shahnaz SubhanChapter 15 The Potential Brain Health Benefits of Royal JellyNoriko Hattori, Yukio Narita, Kenji Ichihara, Hiroyoshi Moriyama, and Debasis BagchiChapter 16 Quorum Sensing-Disrupting Compounds Derived from Plants: Novel Phytotherapeutics to Control Bacterial InfectionsKartik Baruah, Tom Defoirdt, Parisa Norouzitallab, and Peter BossierSection III Molecular MechanismsChapter 17 Interaction of Phytopharmaceuticals with Neurotransmitters in the BrainLeah Mitchell-Bush, Jenaye Robinson, Odochi I. Ohia-Nwoko, Emily Kawesa-Bass, Benjamin A. Stancombe, Catherine A. Opere, Ya Fatou Njie-Mbye, and Sunny E. OhiaChapter 18 Modulation of Neuroprotective Genes by Bioactive Food Components in Senescence-Accelerated MiceShigeru Katayama and Soichiro NakamuraChapter 19 Phytochemicals as Antiaggregation Agents in Neurodegenerative DiseasesEva S.B. Lobbens and Leonid BreydoChapter 20 Synergism among Natural Products in Nueroprotection and Prevention of Brain CancerDarakhshanda Neelam, S.A. Husain, Tanveera Tabasum, and M. Maqbool LoneChapter 21 Deconstructing the Mechanisms of Bioactives from Food Plants in the Management of Alzheimer’s DiseaseZaina Bibi Ruhomally, Shameem Fawdar, Vidushi Shradha Neergheen-Bhujun, and Theeshan BahorunChapter 22 Amyloid β Immunotherapy: An OverviewSuhail Rasool and Charles GlabeSection IV AutismChapter 23 Nutrition and Dance Movement Psychotherapy as Positive and Effective Interventions for Autism in CyprusIndex

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