Kropp & själ
Phosphoinositide 3-kinase in Health and Disease
Christian Rommel • Bart Vanhaesebroeck • Peter K Vogt
Inbunden
4009:-
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From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here we give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here
- Format: Inbunden
- ISBN: 9783642136627
- Språk: Engelska
- Antal sidor: 310
- Utgivningsdatum: 2010-10-01
- Förlag: Springer-Verlag Berlin and Heidelberg GmbH & Co. K