Pharmacology of Potassium Channels

Inbunden, Engelska, 2021

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The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge.

Produktinformation

Utgivningsdatum2021-09-28
Mått155 x 235 x undefined mm
FormatInbunden
SpråkEngelska
SerieHandbook of Experimental Pharmacology
Antal sidor545
FörlagSpringer Nature Switzerland AG
ISBN9783030840518

Tillhör följande kategorier

Biovetenskap inom Naturvetenskap och teknik
Farmakologi inom Medicin
Fysiologi inom Medicin

Comparison of K+ Channel families.- High-resolution structures of K+ channels.- Pharmacological approaches to studying potassium channels.- Cardiac K+ channels and channelopathies.- Cardiac hERG K+ channel as safety and pharmacological target.- Pharmacology of A-type K+ channels.- Kv7 channels and hyperexcitability disorders.- Pharmacological activation of neuronal voltage-gated Kv7/KCNQ/M-channels for potential therapy of epilepsy and pain.- Potassium channels in cancer.- Kir channel molecular physiology, pharmacology and therapeutic implications.- The pharmacology of ATP-sensitive K+ channels (KATP).- Calcium-activated K+ channels (KCa) and therapeutic implications.- The Pharmacology of two-pore domain potassium channels.- Control of biophysical and pharmacological properties of potassium channels by ancillary subunits.- Peptide toxins targeting KV channels.- Therapeutic antibodies targeting potassium ion channels.