Pharmacological Treatment of Alzheimer's Disease

Molecular and Neurobiological Foundations

Inbunden, Engelska, 1997

Av Brioni, Decker, Jorge D. Brioni, Michael W. Decker, Jorge D Brioni, Michael W Decker

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Prominent Alzheimer's investigators provide a comprehensive and balanced overview of the neuropharmacological basis for therapeutics in this devastating disease. Divided into three parts, the book begins with basic research on the neurobiology of cognitive function, offering relevant information on the way the brain encodes and stores data. The second segment explores the molecular aspects of Alzheimer's Disease (AD), emphasizing investigations of possible etiological factors. In the final section, a variety of issues important in developing treatments are discussed including cholinergic-based treatments, the role of neuroinflammin in AD and the therapeutic potential of anti-inflammatory agents.

Produktinformation

Utgivningsdatum1997-03-21
Mått165 x 242 x 33 mm
Vikt992 g
FormatInbunden
SpråkEngelska
Antal sidor549
FörlagJohn Wiley & Sons Inc
ISBN9780471167587

Tillhör följande kategorier

Klinisk psykologi inom Medicin
Neurologi och klinisk neurofysiologi inom Medicin
Farmakologi inom Medicin

Partial table of contents: NEUROBIOLOGY OF COGNITION. Structure and Dynamics of Multiple Memory Systems in Alzheimer's Disease (R. Kesner & M. Ragozzino). Monoamine and Acetylcholine Influences on Higher Cognitive Functions in Nonhuman Primates: Relevance to the Treatment of Alzheimer's Disease (A. Arnsten & C. van Dyck). Neuropsychological Features of Alzheimer's Disease (D. Salmon). MOLECULAR ASPECTS OF ALZHEIMER'S DISEASE. Normal Brain Aging and Alzheimer's Disease Pathology (R. Grewal & C. Finch). Neurofibrillary Tangles in Alzheimer's Disease: Clinical and Pathological Implications (C. Clark, et al.). ALZHEIMER'S DRUG DISCOVERY AND DEVELOPMENT. Use of CSF-Based Markers in the Diagnosis of Alzheimer's Disease (P. Seubert, et al.). Development of Muscarinic Agonists for the Symptomatic Treatment of Alzheimer's Disease (J. Jaen & R. Schwarz). Conceptual Issues in Research on Inflammation and Alzheimer's Disease (J. Rogers). Index.