Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications

Häftad, Engelska, 2012

Av J.-C. Fruchart, Antonio M. Gotto Jr., Rodolfo Paoletti, B. Staels, Alberico L. Catapano, J. -C Fruchart, Antonio M. Gotto Jr, J. -C. Fruchart

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Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control.

Produktinformation

Utgivningsdatum2012-10-14
Mått155 x 235 x 11 mm
Vikt306 g
FormatHäftad
SpråkEngelska
SerieMedical Science Symposia Series
Antal sidor172
FörlagSpringer-Verlag New York Inc.
ISBN9781461354277

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Farmakologi inom Medicin

1. Peroxisome Proliferator Activated Receptor Alpha Coordinates Intermediary Metabolism During Fasting.- 2. Design, Structure, and Function of Novel PPAR Ligands.- 3. Functions of PPAR Gamma in Macrophages and Atherosclerosis.- 4. PPARs and Atherogenesis: Mediators or Modulators of the Inflammatory Response in the Vessel Wall?.- 5. Role of PPARs in Inflammation, Atherosclerosis, and Thrombosis.- 6. Effects of Thiazolidinediones on Vascular Reactivity and Endothelial Dysfunction.- 7. Activation of Human PPAR Subtypes by Pioglitazone.- 8. PPAR? Mechanism of Action Studies.- 9. The Role of PPAR? in Fatty Acid Metabolism and Hepatocarcinogenesis: Studies with PPAR?-Null Mice.- 10. PPAR?, Lipoprotein Metabolism, Metabolic Disease, and Atherosclerosis.- 11. PPAR? and Atherosclerosis.- 12. Regulation of CD36 by PPAR?: Pro- or Anti-atherogenic?.- 13. Anti-inflammatory Properties of High Density Lipoproteins.- 14. The Low-HDL Syndrome: Epidemiology and Pathophysiology.- 15. Diabetes: A Growing CHD Epidemic.- 16. Influence of PPARs on Muscle Lipid Metabolism and Insulin Resistance.- 17. PPAR? in Adipogenesis and Insulin Resistance.- 18. Pharmacology of a Selective Peroxisome Proliferator-Activated Receptor ? Agonist, GW501516, in Obese Dyslipidemic Primates.- 19. PPAR?: A Regulator of Growth and Differentiation.- 20. Peroxisome Proliferator Activator Receptor Gamma Agonists Inhibit the Development of Atherosclerosis in Low Density Lipoprotein Receptor-Deficient Male Mice.- 21. Are Thiazolidinediones Superior to Standard Therapy in the Treatment of Type 2 Diabetes?.- 22. PPAR? Ligands and Intestinal Inflammation.- 23. Inflammatory Mechanisms in Alzheimer’s Disease: ?-Amyloid-Stimulated Proinflammatory Responses Are Blocked by PPAR? Agonists.