Peritoneal Tumor Microenvironment of Cancers on Cancer Hallmarks

Yong Sang Song, MD, PhD is currently Professor at Seoul National University, College of Medicine. He received his MD and PhD at the Seoul National University (1983 and 1994 respectively). He was elected as the chairperson of Korean Society of Urogynecology in 2006. He was selected as the Director of Cancer Research Institute at Seoul National University in 2009, and as the President of Korean Society of Cancer Prevention in 2012. He served as the President of International Society of Precision Cancer Medicine (ISPCM) in 2018. His major research interests are molecular mechanisms of tumors, especially the role of tumor microenvironment in cancer cell metabolism, chemoresistance and precision medicine in gynecologic cancer. He is particularly interested in the impact of components of tumor microenvironment in ovarian cancer progression. Danny N. Dhanasekaran, PhD, is Samuel Roberts Noble Foundation Endowed Chair in Cancer Research. He is Deputy Director for Basic Sciences and Director, SCC-COBRE & Center for Basic Cancer Research, Stephenson Cancer Center, University of Oklahoma Health Science Center, USA. Danny N. Dhanasekaran, PhD, is Samuel Roberts Noble Foundation Endowed Chair in Cancer Research. He is Deputy Director for Basic Sciences and Director, SCC-COBRE & Center for Basic Cancer Research, Stephenson Cancer Center, University of Oklahoma Health Science Center, USA. Benjamin K Tsang, PhD, is director of Reproductive Biology Unit, professor of Obstetrics & Gynecology and Cellular & Molecular Medicine; Life Research Institute, Interdisciplinary School of Health Sciences, Professor Emeritus, University of Ottawa; Senior Scientist, Chronic Disease Program, Emeritus Senior Scientist, Ottawa Hospital Research Institute. Johji Inazawa, MD, PhD, is director/ specially appointed Professor, Research Core Center, Tokyo Medical and Dental University (TMDU), Emeritus Professor, TMDU, Japan. Massoud Mirshahi, MD, PhD, is Professor, Research INSERM unit, Paris 7 University Paris Diderot, France. Marc Pocard, MD, PhD, is Director Research INSERM unit, and Professor, Abdominal and Oncologic Surgery, Paris 7 University Paris Diderot, France. Professor Ciro Isidoro, Clinical Biochemistry and Clinical Molecular Biology, and Professor of Medical Oncology in the Department of Health Sciences, University of Piemonte Orientale, Italy.

• 1. What is the tumor microenvironment?2. Clinical significance of peritoneal cancers3. Tumor microenvironment of peritoneal carcinomatosis: the concept of premetastatic niche altered before tumor implantation4. Cellular models for peritoneal cancer research5. Metabolism of cancer cells altered in peritoneal tumor microenvironment6. Cell-to-cell interactions in peritoneal tumor microenvironment7. Diagnostic, prognostic, and therapeutic biomarkers of ovarian cancer8. Current and future perspectives of xenograft models of human ovarian cancer9. Tumor microenvironment and chemoresistance10. Tumor microenvironment and metastatic progression of cancer11. Role of microbiome and microbial extracellular vesicles in tumor microenvironment12. Tumor evolution during chemotherapy13. Tumor evolution during metastasis14. Future perspective: identification and validation of biomarkers using liquid biopsy