Peptidomics

Mikhail Soloviev is a Senior Lecturer in Biological Chemistry at theRoyal Holloway University of London and serves as the Editor-in-Chiefof the Journal of Nanobiotechnology. CHRIS SHAW is a Professor in DrugDiscovery in the School of Pharmacy at Queen's University in Belfast.PER ANDRéN is an Adjunct Professor in the Department of Pharmaceutical Biosciences at Uppsala University in Sweden.

• SECTION 1: STUDIES OF NATURALLY OCCURRING PEPTIDES. Chapter 1: Analysis of the peptidomes of amphibian skin granular gland secretions - an integrated functional genomic strategy (Chris Shaw, and Tianbao Chen).Chapter 2: A short history of insect (neuro)peptidomics - A personal story of the birth and youth of an excellent model for studying peptidome biology (Peter D.E.M. Verhaert, Martijn W.H. Pinkse, Maria C. Prieto-Conaway, and Markus Kellmann).Chapter 3: Peptidomics of short linear cytolytic peptides from spider venom (Sergey A. Kozlov, Alexander A. Vassilevski, and Eugene V. Grishin).Chapter 4: Molecular cloning approaches to peptidomics: the identification of novel cDNAs encoding neurotoxin-like peptide pools (Zhensheng Pan, Richard Barry, and Mikhail Soloviev).Chapter 5: Wheat antimicrobial peptides (Tatyana I. Odintsova, and Tsezi A. Egorov).Chapter 6: Immunopeptidomics: Applications to dissect immune responses through proteomic-based approaches (Ernesto Oviedo-Orta, and Alexandra Bermudez-Fajardo).Chapter 7: Strategies for reliable and improved identification of peptides (Karl Skuld, Maria Folth, Marcus Svensson, Anna Nilsson, Per Svenningsson, and Per E. Andrun).SECTION 2: PEPTIDOMICS METHODS AND NEW DEVELOPMENTS.Chapter 8: Peptidomics approach to proteomics (Petra Zarbig, and Harald Mischak).Chapter 9: The importance of sample handling in neuropeptidomics (Karl Skuld, Marcus Svensson, Anna Nilsson, Maria Folth, Per Svenningsson, and Per E. Andrun).Chapter 10: Affinity peptidomics and protein microarrays: application to forensics and biometrics (Julian Bailes, and Mikhail Soloviev).Chapter 11: Selective depletion and enrichment methods for the analysis of protein and peptide pools (Paul Finch, and Mikhail Soloviev).Chapter 12: Detection of target peptides in foods and feeds by mass spectrometry (Mireia Fernandez Ocaca).Chapter 13: Quantification of Polypeptides by Mass Spectrometry (Pedro R. Cutillas).SECTION 3: PEPTIDOMICS APPROACH TO BIOMARKER DISCOVERY.Chapter 14: Biomarker discovery (Petra Zarbig, and Harald Mischak).Chapter 15: Can peptidomics provide a useful approach for the identification of biomarkers of toxicological exposure or effect (Helen Griffiths)?Chapter 16: Peptidomics in Neuroendocrine research: a Caenorhabditis elegans and Mus musculus study (Kurt Boonen, Steven J. Husson, Geert Baggerman, Anja Cerstiaens, Walter Luyten, and Liliane Schoofs).CONCLUSION.Chapter 17: Peptidomics and Biology: two scientific disciplines driving each other (Chris Shaw, and Peter D.E.M. Verhaert).

"This volume provides an ample and up-to-date view about this maturing field…" (Quarterly Review of Biology, December 2008)