Pediatric Neurogastroenterology

Christophe Faure, MDCHU Sainte-JustineDivision of Pediatric Gastroenterology, Hepatology and NutritionMontreal, QuebecCanadaNikhil Thapar, MD, PhDUCL Institute of Child Health, Great Ormond Street Hospital NHS Foundation Trust Division of Neurogastroenterology and Motility, Department of Paediatric GastroenterologyLondonUKCarlo Di Lorenzo, MDNationwide Children’s HospitalDivision of Pediatric Gastroenterology, Hepatology, and NutritionColumbus, OHUSA

• Introduction.- Development of the Enteric Neuromuscular System.- Development of Gut Motility.- Visceral Sensitivity.- The Microbiome in Neurogastroenterology.- Integration of Biomedical and Psychosocial Issues in Pediatric Functional Gastrointestinal and Motility Disorders.- Esophageal Manometry.- Antroduodenal Manometry.- Colonic Manometry.- Anorectal Manometry.- Assessment of Feeding and Swallowing Disorders.- Esophageal pH and Impedance Monitoring.- Barostat and Other Sensitivity Tests.- Radionuclide Gastrointestinal Transit Tests.- Electrogastrography, Breath Tests, Ultrasonography, Transit Tests, and SmartPill.- Autonomic Nervous System Testing.- Pathology of Enteric Neuromuscular Disorders.- Genetics of Motility Disorder: Gastroesophageal Reflux, Triple A Syndrome, Hirschsprung Disease, and Chronic Intestinal Pseudo-Obstruction.- Allergy and Neurogastroenterology.- Swallowing and Oropharyngeal Disorders.- Esophageal Achalasia.- Other Esophageal Motility Disorders.- Gastric MotorDisorders.- Pediatric Chronic Intestinal Pseudo-Obstruction.- Hirschsprung Disease.- Motility Problems in Developmental Disorders: Cerebral Palsy, Down Syndrome, Williams Syndrome, Autism, Turner’s Syndrome, Noonan’s Syndrome, Rett Syndrome and Prader Willi.- Familial Dysautonomia and Mitochondrial Disorders.- Esophageal Atresia.- Anorectal Malformations.- Motility After Small Bowel and Colonic Surgery.- Gastric Function After Fundoplication.- Rome Criteria for Functional Gastrointestinal Disorders.- Infant Regurgitation and Pediatric Gastroesophageal Reflux Disease.- Infant Colic.- Functional Diarrhea in Toddlers (Chronic Nonspecific Diarrhea).- Functional Dyspepsia.- Irritable Bowel Syndrome.- Functional Abdominal Pain.- Cyclic Vomiting Syndrome: Comorbidities and Treatment.- Aerophagia.- Rumination Syndrome.- Functional Constipation in Children.- Fecal Incontinence in Children.- Drugs Acting on the Gut: Prokinetics, Antispasmodics, Laxatives.- Drugs That Work in the Brain.- Electrical Stimulation of the GI Tract.- Cognitive Behavioral Therapy for Functional Gastrointestinal Disorders.- Complementary and Alternative Treatments for Motility and Sensory Disorders.- Cellular Based Therapies for Pediatric GI Motility Disorders.- Chronic Intestinal Pseudo-Obstruction Syndrome: Surgical Approach and Intestinal Transplantation.

“This is a comprehensive and up-to-date review as well as practical guide to the diagnosis and treatment of pediatric gastrointestinal motility and functional disorders. … This is a valuable resource for pediatric gastroenterologists, adult gastroenterologists, pediatricians, and all professionals involved in the treatment and management of children with such disorders. … This book also includes many instructive illustrations, photographs, and tables that are very helpful in describing conditions related to this field of medicine.” (Brenton Rogers, Doody's Book Reviews, March, 2017)