This book constitutes the proceedings of the 18th Mexican Conference on Pattern Recognition, MCPR 2026, held in Ciudad Juárez, Mexico, during June 24–27, 2026.The 34 full papers presented in this volume were carefully reviewed and selected from 58 submissions. The papers are organized into the following topical sections: Pattern Recognition and Machine Learning Techniques; Deep Learning and Neural Networks; Computer Vision; Language Processing and Recognition; and Medical Applications of Pattern Recognition.