Patient-Specific Induced Pluripotent Stem Cell Models

Generation and Characterization

Häftad, Engelska, 2016

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This volume captures the rapid developments in the field of induced pluripotent stem (iPS) cells, which have provided novel opportunities and approaches both for better understanding a number of human diseases and for developing new platforms for drug development and screening for such diseases.

Produktinformation

Utgivningsdatum2016-08-23
Mått178 x 254 x 21 mm
Vikt721 g
FormatHäftad
SpråkEngelska
SerieMethods in Molecular Biology
Antal sidor368
FörlagHumana Press Inc.
ISBN9781493949731

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Cellbiologi inom Naturvetenskap och teknik

Generation of Patient-Specific Induced Pluripotent Stem Cell from Peripheral Blood Mononuclear Cells by Sendai Reprogramming Vectors.- A Doxycycline-Inducible System for Genetic Correction of iPSC Disease Models.- Generation and Characterization Of Patient-Specific Induced Pluripotent Stem Cell For Disease Modeling.- Modeling Genomic Imprinting Disorders Using Induced Pluripotent Stem Cells.- Generation and Characterization of Induced Pluripotent Stem Cells from Patients with mtDNA Mutations.- Skin Biopsy and Patient-Specific Stem Cell Lines.- Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells.- Using Human Induced Pluripotent Stem Cells to Model Skeletal Diseases.- Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes.- Calcium Imaging in Pluripotent Stem Cell-Derived Cardiac Myocytes.- Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization of Cardiac Cells.- Differentiation of Human Pluripotent Stem Cells to Cardiomyocytes Under Defined Conditions.- Generation of Cardiomyocytes from Pluripotent Stem Cells.- Generation and Characterization of Patient-Specific iPSC-Model for Cardiovascular Disease.- Transgene-Free Disease-Specific iPSC Generation from Fibroblasts and Peripheral Blood Mononuclear Cells.- Generation and Neuronal Differentiation of Patient-Specific Induced Pluripotent Stem Cells Derived from Niemann-Pick Type C1 Fibroblasts.- Multisystemic Disease Modeling of Liver-Derived Protein Folding Disorders Using Induced Pluripotent Stem Cells (iPSCs).- In Vitro Modeling of Alcohol-Induced Liver Injury Using Human Induced Pluripotent Stem Cells.- Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population.- Modeling Axonal Phenotypes with Human Pluripotent Stem Cells.- Mitochondrial Disease-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization.- Patient-Specific Induced Pluripotent Stem Cell Models: Characterization of iPS Cell-Derived Cardiomyocytes.- Generation of Integration-Free Patient Specific iPS Cells Using Episomal Plasmids Under Feeder Free Conditions.