Pathophysiology of Heart Failure

This volume brings together leading basic scientists and clinicians, presenting new approaches to the complex problem of heart failure, involving cardiomyopathic processes and ischemia perfusion injury. The result is a synthesis of information on molecular biology, cellular physiology and structure-function relationships in the cardiovascular system. The role which excess intracellular calcium plays in the genesis of cardiac dysfunction is described as a fundamental mechanism underlying heart failure; one which may lead to improved prevention and treatment. This book is intended for clinical and experimental cardiologists.