Pathology

Oxidative Stress and Dietary Antioxidants

Häftad, Engelska, 2020

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Pathology: Oxidative Stress and Dietary Antioxidants bridges the disciplinary knowledge gap to help advance medical sciences and provide preventative and treatment strategies for pathologists, health care workers, food scientists and nutritionists who have divergent skills. This is important as oxidative stress can be ameliorated with pharmacological, nutraceutical or natural agents. While pathologists and clinical workers understand the processes in disease, they are less conversant in the science of nutrition and dietetics. Conversely, nutritionists and dietitians are less conversant with the detailed clinical background and science of pathology. This book helps to fill those gaps.

Saves clinicians and researchers time by helping them to quickly access the very latest details on a broad range of pathologies and oxidation issues
Combines the science of oxidative stress and the putative therapeutic usage of natural antioxidants in the diet
Includes preclinical, clinical and population studies to help pathologists, nutritionists, dieticians, and clinicians map out key areas for research and further clinical recommendations

Produktinformation

Utgivningsdatum2020-04-29
Mått216 x 276 x undefined mm
Vikt1 110 g
FormatHäftad
SpråkEngelska
Antal sidor432
FörlagElsevier Science
ISBN9780128159729

Tillhör följande kategorier

Folkhälsa och hälsopedagogik inom Medicin
Tillverkningsteknik inom Naturvetenskap och teknik
Biologi inom Naturvetenskap och teknik

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King’s College Hospital and Emeritus Professor of Nutritional Biochemistry at King’s College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King’s College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.

Part 1 Oxidative Stress and Pathology – Updated based on reviewer feedback (authors not confirmed)1. Free radicals: what they are and what they do (author this is an overview of the type of reactive species)2. Connecting free radicals and MRI in pathology3. Superoxide anions and their role in tissue pathologies4. The clinical biochemistry of oxidative stress in pathological conditions (author this is on biomarkers in urine and blood)5. Oxidative stress in the pathology of brain disease: a focus on Parkinson's disease6. Oxidative stress in the pathology of skin disease7. Oxidative stress in the pathology of kidney disease8. Oxidative stress in the pathology of reproductive disorders: a focus on preeclampsia9. Free radicals, oxidative stress and the pathology of liver disease10. Oxidative stress in oral pathologies11. Linking oxidative stress and cancer: a focus on prostate cancer (author to mention many cancers and then focus on one or two)12. Oxidative stress and breast cancer13. Oxidative stress and cardiovascular disease14. Genomics and oxidative stress: Linking DNA methylation15. Nutritional genomics, cardiovascular disease and oxidative stressPart 2 Antioxidants and Pathology16. Anthocyanins as antioxidants and use in bone pathology17. Antioxidant Ruscus species and antioxidant use in tissue pathology18. Antioxidant ziziphus jujuba and use in pathology19. Ascorbic acid as an antioxidant and applications to the CNS20. Castanea sativa species and antioxidant use in tissue pathology21. Cinnamic acids and use as an antioxidant22. Copaiba oil as an antioxidant and use in liver pathology23. Coriandrum sativum as an antioxidant and cancer protection24. Curcumin and related antioxidants and applications to tissue pathology25. Dietary antioxidant capacity and the ultimate marker of pathology- mortality26. Ellagic acid: sources and uses in the pathology of cancer27. Epigallocatechin gallate (EGCG) as an antioxidant and use in pathology (this must be a new review not published before and coverage of many aspects of EGCG28. Luteolin as an antioxidant and cellular pathology29. Mediterranean diet: antioxidant components and uses in liver pathology30. Methylsulfonylmethane as an antioxidant and use in pathology31. Polyphenolic foods: applications as antioxidants to tissue pathology32. Pomegranate extract as an antioxidant and use in pathological condition33. Resveratrol as an antioxidant and use in pathological condition34. Selenium: role in antioxidant status and use in inflammatory pathologies35. Tocopherol usage, antioxidant effects and pathology of diabetes36. Trace elements and antioxidant effects in pediatric pathology37. Vitamin C as an antioxidant and cardiovascular disease

"The concept of a quick reference combining research in disease progression and disease prevention is very appealing and exciting to many scientists and healthcare workers in preventive care. The author thoroughly explains the pathology of oxidative stress and many diseases relevant to practicing healthcare workers, including cardiovascular disease, diabetes, pulmonary diseases, and cancers. The chapters discussing the relationship between dietary antioxidants and diseases are very specific and may limit which areas of nutrition and medicine can find this textbook useful. A future edition focusing on specific diseases and antioxidant classes and categories would be beneficial to practicing healthcare workers." --Doody