Pathogen Genomics

• I Viruses.- 1 Antiviral Drug Target Discovery with DNA Microarrays.- 2 Chipping Away at HIV Pathogenesis.- 3 Microarray Analysis of Human Papillomavirus Pathogenesis.- 4 Ribozymes as Gene Therapeutic Agents for HIV/AIDS: A Potential Paradigm Shift.- II Bacteria.- 5 Genomics and New Technologies Applied to Antibacterial Drug Discovery.- 6 Genomics of the Mycobacterium tuberculosis Complex and BCG Vaccines.- 7 Bacterial “Genes-to-Screens” in the Post-Genomic Era.- 8 DNA Microarray Expression Analysis in Antibacterial Drug Discovery.- 9 The Influence of Genomics on the Molecular Epidemiology of Nosocomial Pathogens.- 10 Borrelia Genomics as a Tool for Studying Pathogenesis and Vaccine Development.- III Fungi.- 11 Antifungal Target Discovery and Evaluation: Lessons from Saccharomyces cerevisiae.- 12 Antifungal Drug Discovery: Old Drugs, New Tools.- 13 Cryptococcus neoformans: A Molecular Model for the Study of Fungal Pathogenesis and Drug Discovery in the Genomic Era.- 14 Antifungal Target Selection in Aspergillus nidulans: Using Bioinformatics to Make the Difference.- 15 Functional Genomics of Histoplasma capsulatum: Dimorphism and Virulence.- 16 Gene Finding in Coccidioides immitis: Searching for Immunogenic Proteins.- IV Protozoa.- 17 Toxoplasma gondii: A Model for Evolutionary Genomics and Chemotherapy.- 18 The Molecular Biology and Pathogenicity of Entamoeba histolytica.

"As a result of this comprehensive genomic information relying on new technologies and experimental tools, a novel quality in understanding pathogenicity has been reached. This is illustrated in the book in an impressive manner." -Proteomics