In this issue of Critical Care Nursing Clinics, guest editor Lynn C. Parsons of Morehead State University brings her considerable expertise to the topic of Pain Management. Top experts provide up-to-date clinical information and best practices needed for critical care nurses to provide safer and more effective options for pain control. Clinical reviews include topics on chronic post-surgical pain, managing pain in the era of opioid abuse, as well pain management in children, older adults, and orthopedic patients.