Paclitaxel

Mallappa Kumara Swamy, PhD, completed his Postdoctoral Research at the Department of Crop Science, Faculty of Agriculture, Universiti Putra Malaysia (UPM), from 2014-2018. He has more than 16 years of teaching and research experience in the fields of plant biotechnology, secondary metabolites production, phytochemistry and bioactive studies. Dr. Swamy has published more than 100 research publications in peer- reviewed journals, 25 book chapters and has edited 10 books with reputed international publishers. His research focuses on the area of natural products, plant cell, tissue culture technology for bioactive compounds production and evaluation of their bioactivities, and nanobiotechnology for medical applications. T. Pullaiah earned his PhD from Andhra University and then pursued a postdoctoral fellowship at Moscow State University (1976–1978). He is a former Professor of Botany at Sri Krishnadevaraya University, where he taught for more than 35 years. He served as president of the Indian Botanical Society in 2014 and of the Indian Association for Angiosperm Taxonomy in 2013. His honors include the Panchanan Maheshwari Gold Medal, the Prof. P. C. Trivedi Medal, the Dr. G. Panigrahi Memorial Lecture Award of the Indian Botanical Society, and the Prof. Y. D. Tyagi Gold Medal of IAAT. A prolific author and editor, Prof. Pullaiah has mentored students throughout his career and, for several years, has also been a member of the IUCN Species Survival Commission, a global network of over 10,000 volunteer experts dedicated to conserving biodiversity and preventing species extinction through science-based action and collaboration.Zhe-Sheng Chen, PhD, opened the St. John’s University’s first cancer pharmacology laboratory. His research interest is multidrug resistance and its reversal, novel anti-cancer drug development. Chen has over 170 papers published, co-edited Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy book (Elsevier), and holds 5 patents.

• 1. About Cancers and treatment options- An update2. Paclitaxel: Chemistry, synthetic analogues and their anticancer properties3. Taxol: Mechanisms of action against cancer, an update with current research4. Novel forms of Paclitaxel for an effective cancer cure5. Clinical pharmacology of Paclitaxel6. Strategies for enhancing bioavailability of Paclitaxel for cancer treatment7. Application of nanocarriers for Paclitaxel delivery and chemotherapy of cancer8. Paclitaxel: Cancer chemotherapy evidences, advantages, and future directions9. Anticancer Drug Paclitaxel producing plants. Their taxonomy, morphology, identification, distribution and other botanical details (it also includes color photographs of plants)10. Propagation and Micropropagation of Paclitaxel producing plants11. Biotechnology of Paclitaxel producing plants (Paclitaxel production through hairy root cultures, suspension cultures, callus cultures etc)12. Endophytes for the production of anticancer drug, Paclitaxel13. Metabolic engineering strategies to enhance the production of anticancer drug, Paclitaxel14. Paclitaxel and Chemoresistance Chapter15. Overcoming Paclitaxel Resistance16. Paclitaxel and Lung Cancer Treatment17. An update on paclitaxel treatment in Breast cancer-pros and cons