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David Vaudry, Hitoshi Hashimoto - PACAP, Häftad

Häftad, Engelska, 2026

Del i serien Molecular Mediators in Health and Disease: How Cells Communicate

PACAP

From Discovery to Function

Av David Vaudry, Hitoshi Hashimoto

2569 kr

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Beskrivning
PACAP: From Discovery to Function in Health and Disease serves as a comprehensive review covering all aspects of PACAP and its receptors, from expression to function in healthy tissues and disease models. The book introduces the biochemical, pharmacological and signaling properties of PACAP before exploring the biological actions of PACAP in normal health and pathological conditions. It considers PACAP in relation to various aspects, including pain, stress, brain injury, tumor cells and neurodegenerative disease. Effect on peripheral organs is also covered, from the gastrointestinal tract and cardiovascular system to immune cells and bones, among others. Therapeutic potential is also explored. This is a volume in the Molecular Mediators in Health and Disease book series, and provides a complete analysis of PACAP and the latest research in the field. Thus it is an ideal guide for researchers interested in PACAP and its impact across health and disease.

  • Provides a comprehensive overview of PACAP from a molecular, biochemical and pharmacological standpoint
  • Covers the effects of PACAP across a range of peripheral organs including the eye, liver, and respiratory system
  • Explores PACAP in the context of various conditions including neurodegenerative diseases and psychiatric disorders
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David Vaudry specialises in cell biology and neuroscience. After completing his PhD in 2000, he went on to post-doc training in the laboratory of Dr Lee E. Eiden. Since 2002 he has been a researcher at INSERM, France, where, from 2008-2021 he has led the research team centred on ‘Neuropeptides, Neuronal Death and Cell Plasticity’. Since 2020 he has been Editor in Chief of the journal Neuroendocrinology. He is the author of 187 original articles, books and book chapters referenced in PubMed. He has supervised 14 PhD students and is known internationally for his work on the neurotrophic and neuroprotective effects of PACAP. Hitoshi Hashimoto received physiological chemistry training and holds a PhD from Kyoto University. In 1991, he became Assistant Professor at Osaka University, and since 2010 he has been a Professor and Chair of the Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University. He is the author of 248 original articles referenced in PubMed. He is one of the leading researchers known for research on the role of PACAP in the brain, particularly in psychiatric disorders, and has recently widened his research area to investigate neurological mechanisms using a whole-brain imaging system, block-FAce Serial microscopy Tomography (FAST) and an array of neuroscience methods.

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