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Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation.
No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in all biological settings and situations.
In this embattled terrain, the most we can hope for from the biomaterials we design is a type of "meso-compatibility,� a material which can remain functional and benign for as long as required without succumbing to this cellular onslaught and inducing a local inflammatory reaction.
Giuseppe Perale, J�ns Hilborn, Jöns Hilborn, Austria) Perale, Giuseppe (Professor of Regenerative Medicine, Faculty of Biomedical Sciences, University of Southern Switzerland (USI), Switzerland; Visiting Professor, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Sweden) Hilborn, Jons (Department of Materials Chemistry, Uppsala University, Jons Hilborn
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Roger Narayan, USA) Narayan, Roger (Joint Department of Biomedical Engineering, North Carolina State University, NC, Roger J. Narayan
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Traian Chirila, Damien Harkin, Australia) Chirila, Traian (Queensland Eye Institute, Australia) Harkin, Damien (Centre for Vision and Eye Research, Queensland University of Technology, Queensland
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Daniel L Mooradian, USA) Mooradian, Daniel L (University of Minnesota, Minneapolis, MI, Daniel L. Mooradian
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