Oxidative Stress and Antioxidants

This book provides a comprehensive overview of the principles, molecular mechanisms, and biomedical implications of oxidative stress and antioxidant defense systems. The chapters cover the fundamentals of oxidative stress, the sources and types of reactive oxygen and nitrogen species, and the cellular antioxidant defense mechanisms. The book further explores the role of non-enzymatic antioxidants such as vitamins, minerals, and plant polyphenols for their therapeutic potential in health and disease. Additionally, the book reviews oxidative stress-related pathologies including diabetes, cardiovascular diseases, neurodegenerative disorders, cancer, inflammation, and aging. The volume also examines the regenerative role of antioxidants in wound healing and reproduction and discusses environmental toxins as triggers of oxidative imbalance. Towards the end, the book provides insights into therapeutic strategies using antioxidants.Key Features:Examines the biology of oxidative stress, the generation of reactive species, and the mechanisms of cellular redox signalingReviews oxidative stress biology, reactive species generation, and cellular redox signalingHighlights the role of dietary antioxidants, plant polyphenols, and micronutrients in disease prevention and managementExamines oxidative stress-mediated damage to lipids, proteins, and DNA, and the cellular repair mechanisms involvedDiscusses oxidative stress in major diseases including diabetes, cancer, cardiovascular, neurodegenerative, and inflammatory disordersReviews therapeutic applications of antioxidants and the dual nature of oxidative stress in physiological and pathological contextsThis book is intended for researchers and students of biomedical sciences, molecular biology, and pharmaceutical sciences.