Oxidative Neural Injury

• Reactive Oxygen Species, Synaptic Plasticity, and Memory.- Nitric Oxide Biochemistry: Pathophysiology of Nitric Oxide-Mediated Protein Modifications.- Redox Imbalance in the Endoplasmic Reticulum.- Exocytosis, Mitochondrial Injury and Oxidative Stress in Neurodegenerative Diseases.- Neuronal Vulnerability to Oxidative Damage in Aging.- Ischemia-Reperfusion Induces ROS Production from Three Distinct Sources.- Alzheimer Disease: Oxidative Stress and Compensatory Responses.- Oxidative Stress Associated Signal Transduction Cascades in Alzheimer Disease.- Nitrated Proteins in the Progression of Alzheimer’s Disease: A Proteomics Comparison of Mild Cognitive Impairment and Alzheimer’s Disease Brain.- Parkinson’s Disease: An Overview of Pathogenesis.- Protein Oxidation Triggers the Unfolded Protein Response and Neuronal Injury in Chemically Induced Parkinson Disease.- Treating Oxidative Neural Injury: Methionine Sulfoxide Reductase Therapy for Parkinson’s Disease.

From the reviews: "This book addresses how oxidative stress contributes to age-related cellular dysfunction particularly in Alzheimer's ischemia, Parkinson's disease, and other neurodegenerative conditions. The book fills a niche, addressing the current molecular understanding of oxidative stress and its role in pathophysiology. ... it is most appropriate for the many neuroscientists around the world contemplating how to identify the next best approach for targeted therapy for several neurodegenerative diseases. ... the book is a good resource for libraries with PhD graduate students and molecular neuroscience laboratories." (Joseph I. Sirven, Doody's Review Service, December, 2009)