Osteosarcoma

Takafumi Ueda, Osaka National Hospital, Orthopaedic Oncology Group, Department of Orthopaedic SurgeryAkira Kawai, National Cancer Center Hospital, Division of Musculoskeletal Oncology

• Part I: Basic Research and Experimental Therapy.-Chapter 1 Genetics of Osteosarcoma.-Chapter 2 Basic Research for Osteosarcoma Lung Metastasis (LM8).-Chapter 3 Immunotherapy for Osteosarcoma.-Part II: Clinical Features.-Chapter 4 Outcome of Treatment for Osteosarcoma of the Extremities over the Last 20 Years: Report from 11 Referral Centers in Japan.-Chapter 5 Osteosarcoma in the Elderly: Clinical Features and Outcome.-Chapter 6 Prognostic Factors for Osteosarcoma Patients.-Part III: Chemotherapy.-Chapter 7 Neoadjuvant Chemotherapy Developed in Japan.-Chapter 8 Neoadjuvant Chemotherapy (OOS-A, B, C, D regimens).-Chapter 9 Caffeine-Potentiated Chemotherapy for Osteosarcoma.-Part IV: Surgery.-Chapter 10 Endoprosthetic Reconstruction for Extremity Osteosarcoma.-Chapter 11 Limb-Salvage Surgery and Reconstruction for Skeletally Immatur Childhood Osteosarcoma: Extendible Endoprostheses.-Chapter 12 Limb-Salvage Surgery for Pelvic OsteosarcomaChapter 13 Management of Postoperative Infection after Limb Salvage Surgery in Osteosarcoma Patients.-Part V: Surgery : Biological Reconstruction.-Chapter 14 Biological Reconstruction for Extremity Osteosarcoma: Long Term Results and Current Concept of Intraoperative Extracorporeal Irradiated Bone Graft (IORBG).-Chapter 15 Biological Reconstruction for Extremity Osteosarcoma:  Pasteurized Autogenous Bone Graft.-Chapter 16 Biological Reconstruction for Extremity Osteosarcoma: Liquid Nitrogen Treated Tumor-Bearing Bone Graft.-Chapter 17 Biological Reconstruction for Extremity Osteosarcoma: Distraction Osteogenesis Technique.-Chapter 18 Limb-Saving Surgery Using In Situ Preparation (ISP) Method.-Part VI: Unresectable / Metastatic Disease.-

“This book describes the multidisciplinary treatment of osteosarcoma as practiced in Japan. … This will most likely be of value to trainees in oncology -- medical, radiation, and surgical -- as well as practitioners in the field. … This is a worthwhile contribution. It is a niche monograph that will be of interest to those in the field who want an update on the techniques and approaches used in Japan.” (Carol Scott-Conner, Doody's Book Reviews, June, 2016)