Organic Chemistry Workbook

Pierre Vogel is Professor of organic chemistry at the EPFL in Lausanne, Switzerland. He has published three books and has co-authored more than 490 publications in the fields of physical organic chemistry, organic and organometallic synthesis, total asymmetric synthesis of natural products of biological interest, catalysis, glycochemistry and bio-organic chemistry.Kendall N. Houk is Saul Winstein Professor at the UCLA. He is an authority on theoretical and computational organic chemistry. His group develops rules to understand reactivity, computationally models complex organic reactions, and experimentally tests the predictions of theory. He collaborates prodigiously with chemists all over the world. He has published nearly 1100 articles in refereed journals and is among the 100 most-cited chemists.

• 1 Equilibria and Thermochemistry 1Answers to Problems 1References 252 Additivity Rules for Thermodynamical Parameters and Deviations 27Answers to Problems 27References 603 The Rates of Chemical Reactions 61Answers to Problems 613.1 Additional Material 793.1.1 The Bell–Evans–Polanyi Theory for Radical Exchanges 793.1.2 The Effect of Reactant Polarizability 803.1.3 The Effect of Exothermicity 823.1.4 The Hammond–Leffler Postulate is a Theorem Demonstrated by the Bell–Evans–Polanyi Theory 833.1.5 The Selectivity/Reactivity Relationship 84References 854 Molecular Orbital Theories 89Answers to Problems 89References 975 Pericyclic Reactions 99Answers to Problems 99Additional Material 148References 1496 Organic Photochemistry 153Answers to Problems 153Additional Material 191References 1927 Catalytic Reactions 197Answers to Problems 197References 2208 Transition-Metal-Catalyzed C—C Bond Forming Reactions 223Answers to Problems 223References 278