Nutritional Genomics

Professor Regina Brigelius-Flohe is the head of the Department of Biochemistry of Micronutrients in the German Institute of Human Nutrition, Potsdam, Germany. Prior to her position in this institute, she worked in industry in the Center of Research of Gruenenthal GmbH and in the Institute for Molecular Pharmacology in Hannover, Germany. Her work has focused on understanding the mechanisms by which small nutrient molecules such as selenium and vitamin E contribute to human health Professor Hans-Georg Joost was made scientific director of the German Institute of Human Nutrition in 2002. Throughout his career he has published more than 100 peer-reviewed papers, with a primary focus on obesity research.

• INTRODUCTION -DEFINITIONSNutritional Genomics: Concepts, Tools and ExpectationsNUTRIGENOMICS (NUTRIENT-GENE INTERACTIONS)Nuclear Receptors: An OverviewMechanism of Action and Cancer Therapeutic Potential of RetinoidsNuclear Receptors and the Control of Gene Expression by Fatty AcidsCellular Adaptation to Amino Acid Availability: Mechanisms Involved in the Regulation of Gene ExpressionTranscriptional Regulation of Hepatic Genes by Insulin and GlucosePPARs: Lipid Sensors that Regulate Cell Differentiation ProcessesAdvances in Selenoprotein Expression: Patterns and Individual VariationsPPARs in AtherosclerosisProtein Synthesis and CancerMutations in the PPAR Gene Relevant for Diabetes and the Metabolic SyndromeRegulation of Lipogenic Genes in ObesityNUTRIGENETICS (NUTRIENT-GENOTYPE INTERACTIONS)The Genetics of Type 2 DiabetesGene Variants and ObesityGene Polymorphisms, Nutrition, and the Inflammatory ResponseGene Variants, Nutritional Parameters, and HypertensionGene Variants, Nutrition, and CancerTaste Receptors and their VariantsCancer and Gene Variants in Enzymes Metabolizing Dietary Xenobiotics

"Die Untersuchung der Wechselwirkung zwischen der Ernährung bzw. den Inhaltsstoffen von Lebensmitteln und dem menschlichen Genom generiert Impulse für die wirtschaftliche Umsetzung wissenschaftlicher Ergebnisse sowohl für die Ernährungsindustrie als auch im Bereich der Prävention ernährungsbedingter Erkrankungen, z. B. in Diagnostika. Das vorgestellte Buch präsentiert die neuesten Erkenntnisse dieses jungen Forschungsgebietes."Umweltjournal "Ein Standardwerk für jeden Ernährungsmediziner und Studierenden der Ernährungswissenschaften und verwandten Fakultäten."Umwelt & Gesundheit