Numerical and Statistical Methods for Bioengineering

Michael R. King is an Associate Professor of Biomedical Engineering at Cornell University. He is an expert on the receptor-mediated adhesion of circulating cells, and has developed new computational and in vitro models to study the function of leukocytes, platelets, stem and cancer cells under flow. He has co-authored two books and received numerous awards, including the 2008 ICNMM Outstanding Researcher Award from the American Society of Mechanical Engineers and received the 2009 Outstanding Contribution for a Publication in the international journal Clinical Chemistry. Nipa A. Mody is currently a postdoctoral research associate at Cornell University in the Department of Biomedical Engineering. She received her Ph.D. in Chemical Engineering from the University of Rochester in 2008 and has received a number of awards including a Ruth L. Kirschstein National Research Service Award (NRSA) from the NIH in 2005 and the Edward Peck Curtis Award for Excellence in Teaching from the University of Rochester in 2004.

• 1. Types and sources of numerical error; 2. Systems of linear equations; 3. Statistics and probability; 4. Hypothesis testing; 5. Root finding techniques for nonlinear equations; 6. Numerical quadrature; 7. Numerical integration of ordinary differential equations; 8. Nonlinear data regression and optimization; 9. Basic algorithms of bioinformatics; Appendix A. Introduction to MATLAB; Appendix B. Location of nodes for Gauss-Legendre quadrature.

'I think this book is a winner … [it] is really easy to read and places frameworks for numerical analysis into realistic bioengineering concepts that students will find familiar and relevant. This is most evident in the excellent boxed examples, but also in many of the homework problems. I also really liked the 'key points to consider' at the end of the chapters - these are useful reminders for the students. Finally, the book presents bioinformatics in a manageable fashion that should help demystify this subject for interested students.' K. Jane Grande-Allen, Rice University