Nucleic Acids in the Gas Phase

• Introduction: Why study Nucleic Acids in vacuo?.- Transferring Nucleic Acids to the Gas Phase.- Structure of Nucleic Acids in the Gas Phase.- Interactions between Nucleic Acid Ions and Electrons and Photons.- Gas-phase Spectroscopy of Nucleic Acids.- Fragmentation Reactions of Nucleic Acid Ions in the Gas Phase.- Characterization of Ribonucleic Acids and their Modifications by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.- Quantification of DNA Damage using Mass Spectrometry Techniques.- Ligand Binding to Nucleic Acids.- MS-based Approaches for Nucleic Acid Structural Determination.

"'Nucleic Acids in the Gas Phase,' edited by Valerie Gabelica, takes on the task of telling the story of how mass spectrometry can reveal important information about these biomolecules, even in a small data format. ... the volume succeeds in its overall goal to expose the reader to the breadth of information that can be gleaned from nucleic acids using mass spectrometry ... . this information advances our understanding and appreciation of nucleic acid structure and function." (Patrick A. Limbach, Journal of The American Society for Mass Spectrometry, Vol. 26, 2015)