Normal and Malignant Hematopoiesis

New Advances

Häftad, Engelska, 2012

719 kr

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''An exciting glance at key issues in contemporary hematopoiesis.'' -The Quarterly Review of Biology

1. Regulation of Normal Hemopoiesis.- 2. Cytokine Regulation of Lymphohemopoietic Progenitors.- 3. Hematopoietic Stem Cells.- 4. Transcriptional Control of Hematopoietic Development: Roles of GATA-Factors.- 5. Rearrangement of the ALL1 Gene in Acute Myeloid Leukemia without Chromosomal Translocations.- 6. Non-Receptor Protein Tyrosine Kinases: Pivotal Regulatory Molecules Controlling Lymphopoiesis.- 7. The Regulation and Function of p21Ras in T Cell Activation and Growth.- 8. Irf-1 Functions as a Tumor Suppressor: Possible Involvement in Human Myelodysplasia and Leukemia.- 9. A Family of High Molecular Weight Proteins Active in Differentiation and Growth Control.- 10. Hematopoietic Signaling by the Cytokine Receptor Superfamily.- 11. Positive and Negative Growth Effects of Abl Genes.- 12. Advances in the Understanding of the Molecular Pathogenesis of Aggressive B Cell Lymphomas.- 13. Structure and Expression Pattern of the PML Gene.- 14. Contribution of the Cyclin D1 Gene to Lymphomagenesis.- 15. Clinical Results of All-trans Retinoic Acid: A Targeted Drug for Differentiation Treatment in Acute Promyelocytic Leukemia.- 16. Induction of Alloantigen Specific T Cell Anergy by Inhibition of the B7:CD28 Pathway.- 17. Novel Strategies for Cancer Treatment through Modulation of Proimmune and Proinflammatory Cytokines.- 18. Concluding Comments.