Del 349 - Current Topics in Microbiology and Immunology

NF-kB in Health and Disease

Häftad, Engelska, 2013

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Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology—from immunity and inflammation to apoptosis, cell survival, growth, and proliferation

Produktinformation

Utgivningsdatum2013-07-15
Mått155 x 235 x 16 mm
Vikt423 g
FormatHäftad
SpråkEngelska
SerieCurrent Topics in Microbiology and Immunology
Antal sidor268
Upplaga2011
FörlagSpringer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN9783642268038

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Onkologi inom Medicin

Preface.- Understanding the Logic of IkappaB:NF-kappaB Regulation in Structural Terms.- IKK regulation and human genetics.- Specialized chromatin patterns in the control of inflammatory gene expression.- Macrophages and NF-kappaB in Cancer.- NF-κB/Rel proteins and the humoral immune responses of Drosophila melanogaster.- IKK and NF-kappaB mediated functions in carcinogenesis.- Control of NF-kappaB activity by proteolysis.- NF-kappaB as a target for oncogenic viruses.- NF-kappaB and Innate Immunity.- Inhibition of NF-kappaB signaling as a strategy in disease therapy.- NF-κB and mucosal homeostasis.- NF-kappaB In liver cancer – the plot thickens.- Subject index.