Next Generation Antidepressants

Chad E. Beyer is Prinicpal Research Scientist II at Pfizer Global Research and Development, Princeton, New Jersey and Adjunct Professor at Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Stephen M. Stahl is Adjunct Professor of Psychiatry at the University of California San Diego, San Diego, California, and Neuroscience Education Institute, Carlsbad, California, USA.

• Preface Chad E. Beyer; 1. Current depression landscape: a state of the field today Laurence Mignon and Stephen M. Stahl; 2. Novel therapeutic targets for treating affective disorders Eliyahu Dremencov and Thomas Cremers; 3. Developing novel animal models of depression Lotte de Groote, Malgorzata Filip and Andrew C. McCreary; 4. Translational research in mood disorders: using imaging technologies in biomarker research Jul Lea Shamy, Adam M. Brickman, Chris D. Griesemer, Anna Parachikova and Mark Day; 5. Defining depression endophenotypes Lisa H. Berghorst and Diego A. Pizzagalli; 6. Genetic and genomic studies of major depressive disorder Roy H. Perlis; 7. Medicinal chemistry challenges in the design of next generation antidepressants David P. Rotella; 8. Application of pharmacogenomics and personalized medicine for the care of depression Keh-Ming Lin, Chun-Yu Chen and Yu-Jui Yvonne Wan; Index.

'This is a very useful and interesting publication with a great deal of clearly summarised information on biological depression research. It gives a concise overview of likely future directions for new treatments.' The British Journal of Psychiatry