The book is the proceedings of the 5th International Conference on Computational Engineering (ICCE 2024), Darmstadt, Germany, 30th September to 2nd October, 2024. Computational Engineering is a modern and ultidisciplinary science for computer based modeling, simulation, analysis and optimization of complex engineering applications and natural phenomena. The book contains an overview of selected approaches from numerics and optimization of Partial Differential Equations as well as uncertainty quantification and machine learning techniques, typically in multiphysics environments. Where possible, application cases from engineering are integrated.