New Generation Vaccines

Inbunden, Engelska, 2009

Av Myrone M. Levine, Myron M. Levine, Gordon Dougan, Michael F. Good, Margaret A. Liu, Gary J. Nabel, James P. Nataro, Rino Rappuoli, USA) Levine, Myron M. (University of Maryland, Baltimore, UK) Dougan, Gordon (The Sanger Institute, Hinxton, Cambridge, USA) Nabel, Gary J. (National Institutes of Health, Bethesda, Maryland, USA) Nataro, James P. (University of Maryland, Baltimore

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Highlighting the latest activities and initiatives of prominent organizations working in the vaccine industry such as the Bill and Melinda Gates Foundation, The Global Alliance for Vaccines and Immunization, WHO, UNICEF, the World Bank, New Generation Vaccines, Fourth Edition, details steps developing countries have taken toward research, development, manufacture, and regulation of several new vaccines for widespread use.This text will:cover the current state-of-the-art techniques in vaccine development – including the successes and the failurestrace vaccine development from the bench to public health with regard to both FDA and European Union regulationsinvestigate improved methods for immunizing large populations, and the use of needless vaccinationsdiscuss the advancements in the heavily government-funded areas for developing vaccines against potential bioterror and infectious disease agents as well as the immunization of large population bases for diseases like: Anthrax, Smallpox, Ebola, West Nile, SARS, and othersUpdated throughout with new cutting-edge information on recent breakthroughs and developments.NEW TO GENERATION VACCINES, FOURTH EDITION:highlights the latest activities of prominent organizations in the vaccine industrycovers the current techniques in vaccine developmentinvestigates improved methods for immunizing large populations

Produktinformation

Utgivningsdatum2009-12-09
Mått210 x 280 x 53 mm
Vikt2 540 g
FormatInbunden
SpråkEngelska
Antal sidor1 040
Upplaga4
FörlagTaylor & Francis Inc
ISBN9781420060737

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Onkologi inom Medicin
Tillverkningsteknik inom Naturvetenskap och teknik
Samhällsmedicin och preventiv medicin inom Medicin
Biologi inom Naturvetenskap och teknik
Infektionssjukdomar och smittsamma sjukdomar inom Medicin

Vaccines and Vaccination in Historical Perspective. An Overview of Biotechnology in Vaccine Initial Clinical Evaluation of New Vaccine Candidates: Investigators' Perspective of Phase I and II Clinical Trials of Safety, Immunogenicity & Preliminary Efficacy Development. Clinical vaccine trials in developing countries Long-Term Evaluation of Vaccine Protection: Methodological Issues for Phase III and IV Studies (including designs to measure herd immunity). Ethical Considerations in the Conduct of Vaccine Trials in Developing Countries Vaccine Economics: From Candidates to Commercialized Products in the Developing World (will include new G8 financing mechanisms). Development and Supply of Vaccines: An Industry Perspective Reaching Every Child - Achieving Equity in Global Immunization A Paradigm for International Cooperation: the Global Alliance for Vaccines and Immunization (GAVI) and the Vaccine Fund Economic Analyses of Vaccines and Vaccination Programs The Role of the Food and Drug Administration and other Industrialized Country Regulatory Agencies in Vaccine Testing and Licensure Strengthening Regulatory Agencies in Developing Countries Developing Safe Vaccines A Primer on Large-Scale Manufacture of Modern Vaccines. Polio Eradication: Ever Closer to a Worthy but Elusive Goal Full Genome Sequence Analysis (Data Mining) and Bioinformatics Overview of Reverse Vaccinology Recent Advances in Immunology that Impact Vaccine Development How the Innate Immune System Affects Adaptive Immune Responses to Vaccines Immunodominance, Deceptive Imprinting & B Cell Mimotopes Standardization and High-Throughput Measurement of T-Cell and B-Cell Responses to Vaccines The Challenge of Inducing Protection in Very Young Infants and the Elderly. Vaccination and Autoimmunity An Overview of Adjuvants for the Future Immune-Enhancing Sequences (CpG Motifs), Cytokines, and Other Immunomodulatory Moieties. Use of Genetically Detoxified Mutants of Cholera and Escherichia coli Hea