This bookcontains a selection of articles from The 2016 World Conference on InformationSystems and Technologies (WorldCIST'16), held between the 22nd and 24th of Marchat Recife, Pernambuco, Brazil. WorldCIST is a global forum for researchers andpractitioners to present and discuss recent results and innovations, currenttrends, professional experiences and challenges of modern Information Systemsand Technologies research, together with their technological development andapplications.The main topicscovered are:  Information and KnowledgeManagement; Organizational Models and Information Systems; Software and SystemsModeling; Software Systems, Architectures, Applications and Tools; MultimediaSystems and Applications; Computer Networks, Mobility and Pervasive Systems; Intelligentand Decision Support Systems; Big Data Analytics and Applications;Human-Computer Interaction;Health Informatics; Information Technologies inEducation; Information Technologies in Radiocommunications.