Neuropsychology of Epilepsy and Epilepsy Surgery

After earning a Ph.D. in Clinical Psychology, Dr. Gregory P. Lee completed postdoctoral fellowships in Neuropsychology at the University of Houston, in conjunction with Baylor College of Medicine, and University of Wisconsin Medical School. He is board-certified in Clinical Neuropsychology by the American Board of Professional Psychology and American Board of Clinical Neuropsychology and is a fellow of the American Psychological Association and National Academy of Neuropsychology. Dr. Lee is a tenured Professor of Neurology in the School of Medicine, School of Allied Health, and School of Graduate Studies at the Medical College of Georgia where he is Director of the Adult Neuropsychology Service, Director of Training for the postdoctoral fellowship program in clinical neuropsychology, and Director of Research in the School of Allied Health. In addition to overseeing neuropsychological services for general neurology, epilepsy, and neurosurgery patients, Dr. Lee performs cortical stimulationmapping, functional magnetic resonance imaging, and intracarotid amobarbital (Wada) procedures for the Epilepsy Surgery Program. Professor Lee is also an active researcher (> 150 publications) primarily in the areas of epilepsy and epilepsy surgery. Dr. Lee has been elected to the Board of Directors of the American Board of Clinical Neuropsychology and serves on the executive committee of the Amercian Board of Professional Psychology.

• PREFACEACKNOWLEDGMENTSPART ONEMEDICAL ASPECTS OF EPILEPSY FOR NEUROPSYCHOLOGISTSChapter 1IntroductionDefinitionsEpidemiologyEtiologyRole of Neuropsychologist in EpilepsyRole of Neuropsychologist in Epilepsy SurgeryChapter 2Classification of Epilepsy DisordersTradition Classification of Seizure DisordersPartial Seizure DisordersSimple Partial SeizuresComplex Partial SeizuresGeneralized Seizure DisordersAbsence SeizuresTonic-Clonic SeizuresEpidemiology of Seizure DisordersEtiology of Seizure DisordersChapter 3Epilepsy SyndromesLocalization-Related EpilepsiesIdiopathic Localization-RelatedSymptomatic Localization-RelatedSymptomatic Reflex EpilepsiesTemporal Lobe EpilepsiesFrontal Lobe EpilepsiesParietal Lobe EpilepsiesOccipital Lobe EpilepsiesCrytogenic Localization-Related EpilepsiesGeneralized Epilepsy SyndromesIdiopathic Generalized SyndromesChildhood Absence EpilepsyJuvenile Absence EpilepsyCryptogenic Generalized Epilepsy SyndromesLennox-Gastaut SyndromeSymptomatic Generalized Epilepsy SyndromesUndetermined Epilepsy SyndromesAcquired Epileptic AphasiaContinuous Spike-Waves during Slow SleepSpecial SyndromesFebrile ConvulsionsIsolated Status EpilepticusEpidemiology of Epilepsy SyndromesEtiology of Epilepsy SyndromesNon-Epileptic SeizuresSudden Unexplained Death in Epilepsy (SUDEP)Chapter 4Diagnostic Tests in EpilepsyElectrophysiologyInterictal Scalp RecordingsEEG Patterns in Partial EpilepsiesEEG Patterns in Generalized EpilepsiesStructural Neuroimaging in EpilepsyChapter 5Medical (Non-Surgical) Treatment of EpilepsyPharmacological TherapiesOlder Antiepileptic DrugsNewer Antiepileptic DrugsAntiepileptic Drug Adverse EffectsAntiepileptic Drugs in WomenPregnancy / Teratogenic EffectsAED Treatment in ChildrenCognitive & Behavioral EffectsReview of Specific Antiepileptic DrugsUse of AEDs in Bipolar DisorderSuicidality and Antiepileptic DrugsKetogenic DietChapter 6Neuropsychological Assessment in EpilepsySelection of Neuropsychological TestsFactors Contributing to Cognitive DeclineConfounding Factors in Test InterpretationCognitive Deficits in EpilepsyAttentionADHDMemoryIntelligenceLanguageVisual-Perceptual & Spatial FunctionsExecutive FunctionsChildhood Learning DisabilitiesQuality of Life AssessmentDriving Issues in EpilepsyCase Example: Preoperative Cognitive TestingChapter 7Psychological and Psychiatric Disorders in EpilepsyRisk FactorsMood DisordersAnxiety DisordersPsychotic DisordersPersonality DisordersInterictal Behavioral Syndrome of TLEEpilepsy-Specific Psychological DisordersChapter 8Psychogenic Nonepileptic Seizures (PNES)Diagnosis2PrevalenceEtiologySymptomsAssessmentTreatmentPART TWO SURGICAL TREATMENT OF EPILEPSYChapter 9Neuropsychological Assessment in Epilepsy SurgeryPreoperative Neuropsychological AssessmentPurposes of Preoperative AssessmentLateralization & LocalizationRisk for Postoperative ImpairmentEstablish a BaselinePrediction of Seizure ControlPostoperative Neuropsyhological AssessmentCase Example: Right Temporal LobectomyChapter 10Other Neuropsychological Procedures in Epilepsy SurgeryIntracarotid Amobarbital (Wada) ProcedureWada Testing in ChildrenFunctional Magnetic Resonance ImagingElectro-Cortical Stimulation MappingCase Example: Wada Predicts AmnesiaChapter 11Medical Aspects of Epilepsy SurgeryCriteria for Surgical EvaluationDiagnostic Evaluation for Epilepsy SurgeryNoninvasive Video-EEG MonitoringMagnetic Resonance Iimaging (MRI)Functional NeuroimagingMonitoring with Intracranial ElectrodesEpilepsy Surgery ProceduresVagus Nerve StimulationAnterior Temporal LobectomyFrontal LobectomyParietal LobecotomyOccipital LobectomyLesionectomyHemispherectomyCorpus CallosotomyMultiple Subpial TransectionSelective AmygdalohippocampectomyImplanted Brain StimulatorsCase Example: Brain Stimulator CandidateAppendix I:Traditional Classification of Epileptic Seizures - Description of Seizure Types Not Covered in TextSimple partial seizures with motor signsSimple partial seizures with somatosensory or special sensory symptomsSimple partial seizures with autonomic symptoms or signsSimple partial seizures with psychic signsSimple partial seizures with cognitive signsSimple partial seizures with affective signsSimple partial seizures with illusionsSimple partial seizures with hallucinationsGeneralized seizure disordersAtypical absence seizuresMyoclonic SeizuresClonic SeizuresTonic SeizuresAtonic SeizuresAppendix II:Classification of Epilepsy Syndromes - Description of Seizure Types Not Covered in TextIdiopathic Localization-RelatedBenign childhood epilepsy with centrotemporal spikesChildhood epilepsy with occipital paroxysmsReading epilepsyHot water epilepsyAutosomal dominant nocturnal frontal lobe epilepsySymptomatic Localization-RelatedRasmussen's syndrome Reflex epilepsiesPhotosensitive seizuresMusicogenic epilepsyEating epilepsyStartle epilepsyFrontal lobe epilepsiesPrecentral frontal lobe seizuresPremotor frontal lobe seizuresSupplementary motor area (SMA) seizuresDorsolateral prefrontal lobe seizuresOrbitofrontal lobe seizuresMedial frontal lobe seizuresFrontal opercular seizuresParietal lobe epilepsiesPostcentral gyrus seizuresSuperior parietal lobule seizuresInferior parietal lobule seizuresParacentral parietal lobe seizuresIdiopathic Generalized Epilepsy SyndromesBenign neonatal familial convulsionsBenign neonatal convulsions (non-familial)Benign myoclonic epilepsy of childhoodJuvenile myoclonic epilepsy (JME)Epilepsy with tonic-clonic seizures upon awakeningCryptogenic or Symptomatic Generalized Epilepsy SyndromesWest syndrome (infantile spasms)Myoclonic-astatic seizuresEpilepsy with myoclonic absencesAppendix III:Wada Assessment Procedures and Rating Criteria at the Medical College of Georgia (MCG)Procedure for measuring Wada language at MCGProcedure for measuring Wada memory at MCGMCG Wada Evaluation scoring formGlossary of Common Epilepsy Terms

"Overall, I recommend this book for neuropsychologists who see epilepsy patients. Its use as a reference will be facilitated after an initial read of the whole book, which will also provide clinicians with a solid overview of the field... the strength of this volume lies in its brevity. I very much liked the short, half to one-page descriptions of syndromes provided in the appendix, and found myself reaching for this book more than once during the reviewprocess to familiarize myself with a specific surgical procedure or refresh my memory of a specific seizure type." -- Christian von Thomsen, Psy.D., Division of Behavioral Medicine and Clinical Psychology,Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA"The book Neuropsychology of Epilepsy and Epilepsy Surgery provides a fabulous overview of epilepsy and seizures that includes diagnosis, etiology, and treatment, with a focus on neuropsychological aspects of the epilepsies and their management. The book is easy to read, and includes tables that nicely summarize a wealth of information...This volume is sure to become a core reference and teaching guide for the neuropsychology of epilepsy for years to come." -- Mike R. Schoenberg, The Clinical Neuropsychologist