Neuroprotection

Method and Protocols

Häftad, Engelska, 2025

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Chapters guide readers through neuropathology, neuroprotection, Alzheimer’s disease, amyotrophic lateral sclerosis, ALS, Huntington’s disease , multiple sclerosis, Parkinson’s disease, spinal cord injury, traumatic brain injury, and ischemic brain injury.

Produktinformation

Utgivningsdatum2025-03-02
Mått178 x 254 x 36 mm
Vikt1 228 g
FormatHäftad
SpråkEngelska
SerieMethods in Molecular Biology
Antal sidor641
FörlagSpringer-Verlag New York Inc.
ISBN9781071636640

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Biovetenskap inom Naturvetenskap och teknik

TUNEL-n-DIFL Method for Detection and Estimation of Apoptosis Specifically in Neurons and Glial Cells in Mixed Culture and Animal Models of Central Nervous System Diseases and Injuries.- Isolation of Capillaries from Small Amounts of Mouse Brain Tissue.- Isolation of Extracellular Vesicles Using Formulas to Adapt Centrifugation to Different Centrifuges.- High-resolution Respirometry for Mitochondrial Function in Rodent Brain.- Quantification of Neuronal Dendritic Spine Density and Lengths of Apical and Basal Dendrites in Temporal Lobe Structures Using Golgi-Cox Staining.- Quantification of Neuroinflammatory Markers in Blood, Cerebrospinal Fluid, and Resected Brain Samples Obtained from Patients.- Targeted Modification of Epigenetic Marks Using CRISPR/Dcas9-Suntag-based Modular Epigenetic Toolkit.- Elevated Plus Maze for Assessment of Anxiety and Memory in Rodents.- Drosophila Neuromuscular Junction as a Model to Study Synaptopathies and Neuronal Autophagy.- Cell-based Assay to Detect the Autoantibody Serostatus in Patients with Neuromyelitis Optica Spectrum Disorder (NMOSD).- Using Small Molecules for Targeting Heavy Metals in Neurotoxicity and Neuroinflammation.- Chromatographic Separation and Quantitation of Sphingolipids from the Central Nervous System or Any Other Biological Tissue.- Role of Network Pharmacology in Prediction of Mechanism of Neuroprotective Compounds.- Role of Serotonergic System in Regulating Brain Tumor-associated Neuroinflammatory Responses.- Impacts of Omega-3 Fatty Acids, Natural Elixirs for Neuronal Health, on Brain Development and Functions.- Microglial Uptake of Extracellular Tau by Actin-mediated Phagocytosis.- Internalization and Endosomal Trafficking of Extracellular Tau in Microglia Improved by α-Linolenic Acid.- Understanding Actin Remodeling in Neuronal Cells Through Podosomes.- Quantitative Investigation of Neuroprotective Role of ROR1in a Cell Culture Model of Alzheimer's Disease.- microRNA Isolation, Expression Profiling, and Target Identification for Neuroprotection in Alzheimer's Disease.- Quantitative Measurement of Tau Aggregation in Genetically Modified Rats with Neurodegeneration.- Detection and Characterization of Apoptosis-related Proteins in Hippocampal Neurodegeneration: From mRNA Expression to Protein Quantification.- Isolation and Detection of Pathological Tau Species in a Tauopathy Mouse Model.- Enzyme Inhibition Assays for Monoamine Oxidase.- Role of Amyloid Beta in Neurodegeneration and Therapeutic Strategies for Neuroprotection.- Amyloid Beta Mediated Neurovascular Toxicity in Alzheimer’s Disease.- Fecal Microbiota Transplantation in Amyotrophic Lateral Sclerosis: Clinical Protocol and Evaluation of Microbiota Immunity Axis.- Integrated Multi-omics Analysis and Validation in Yeast Model of Amyotrophic Lateral Sclerosis.- Imaging and Assay of the Dynamics of Cytotoxic Huntingtin (HTT) Protein Aggregates Regulated by lncRNAs.- Astrocyte Activation and Drug Target in Pathophysiology of Multiple Sclerosis.- Promises of Lipid-based Nanocarriers for Delivery of Dimethyl Fumarate to Multiple Sclerosis Brain.- Chrysin for Neurotrophic and Neurotransmitter Balance in PD.- Establishment of a 6-OHDA Unilateral Lesion Male Wistar Rat Model of Parkinson's Disease.- Evaluating Motor Dysfunction and Oxidative Stress Induced by Trichloroethylene in Wistar Rats.- Neurobehavioral Analysis to Assess Olfactory and Motor Dysfunction in Parkinson’s Disease.- Ion Channels and Metal Ions in Parkinson’s Disease: Historical Perspective to the Current Scenario.- Creating a Reproducible Model of Spinal Cord Injury in Rats: A Contusion Approach.- Weight Drop Method for Inducing Closed Head Diffuse Traumatic Brain Injury.- iDISCO Tissue Clearing Whole-Brain and Light Sheet Microscopy for High-ThroughputImaging in a Mouse Model of Traumatic Brain Injury.- Insights From Rodent Models for Improving Bench-to-Bedside Translation in Traumatic Brain Injury.- Rat Model of Middle Cerebral Artery Occlusion.