Neuropeptides in Neuroprotection and Neuroregeneration

Fred J. Nyberg

• The Neuropeptide Systems—Some Basic Concepts. Neuropeptide Biosynthesis. Neuropeptide Degradation Related to the Expression of Physiological Action of Neuropeptide. Neuropeptides, Isolation, Identification, and Quantitation. Cellular and Molecular Processes of Neuronal Damage and Protective Mechanisms in Neuroprotection and Neuroregeneration. What General Messages Can We Learn from the Situation after Brain Ischemia?. Dynorphins in Central Nervous System Pathology. Postnatal Stress Procedures Induce Long-Term Endocrine and Metabolic Alterations Involving Different Proopiomelanocortin-Derived Peptides. Prothymosin α—A Novel Endogenous Neuroprotective Polypeptide against Ischemic Damages. Influence of Anabolic Androgenic Steroids on Dynorphinergic Pathways in the Rat Brain. Angiotensin II Receptors and Neuroprotection. PACAP and Cellular Protection: Cellular Protection by Members of the VIP/Secretin Family with an Emphasis on Pituitary Adenylate Cyclase-Activating Polypeptide. General Strategies of Peptide Synthesis. Addressing the Interactions between Opioid Ligands and Their Receptors: Classic and Nonclassic Cases. Use of Peptides as Drug Leads—A Case Story on the Development of Dipeptides Corresponding to the Heptapeptide Substance P(1-7), with Intriguing Effects on Neuropathic Pain. Cognition-Enhancing Peptides and Peptidomimetics.